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Deferoxamine Therapy for Hemorrhagic Transformation Following Brain Ischemia.

作者信息

Bah Momodou G, Holste Katherine G, Xi Guohua, Keep Richard F

机构信息

Michigan State University, College of Human Medicine, East Lansing, MI, USA.

Department of Neurosurgery, University of Michigan, 3552 Taubman Center, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5338, USA.

出版信息

Transl Stroke Res. 2024 Dec;15(6):1015-1016. doi: 10.1007/s12975-023-01188-8. Epub 2023 Aug 17.

DOI:10.1007/s12975-023-01188-8
PMID:37587306
Abstract
摘要

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本文引用的文献

1
Overexpression of Mitochondrial Ferritin Enhances Blood-Brain Barrier Integrity Following Ischemic Stroke in Mice by Maintaining Iron Homeostasis in Endothelial Cells.线粒体铁蛋白的过表达通过维持内皮细胞中铁稳态增强小鼠缺血性中风后的血脑屏障完整性。
Antioxidants (Basel). 2022 Jun 26;11(7):1257. doi: 10.3390/antiox11071257.
2
Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management.缺血性卒中后的出血性转化：机制与管理
Front Neurol. 2021 Nov 30;12:703258. doi: 10.3389/fneur.2021.703258. eCollection 2021.
3
Clinical and Imaging Indicators of Hemorrhagic Transformation in Acute Ischemic Stroke After Endovascular Thrombectomy.
血管内血栓切除术后急性缺血性卒中出血转化的临床及影像学指标
Stroke. 2022 May;53(5):1674-1681. doi: 10.1161/STROKEAHA.121.035425. Epub 2021 Dec 7.
4
Targeting Pro-Oxidant Iron with Deferoxamine as a Treatment for Ischemic Stroke: Safety and Optimal Dose Selection in a Randomized Clinical Trial.以去铁胺靶向促氧化铁作为缺血性中风的治疗方法：一项随机临床试验中的安全性和最佳剂量选择
Antioxidants (Basel). 2021 Aug 10;10(8):1270. doi: 10.3390/antiox10081270.
5
Risk factors for intracranial hemorrhage after mechanical thrombectomy: a systematic review and meta-analysis.机械取栓术后颅内出血的危险因素：一项系统评价和Meta分析
Expert Rev Neurother. 2019 Oct;19(10):927-935. doi: 10.1080/14737175.2019.1632191. Epub 2019 Jul 5.
6
Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial.甲磺酸去铁胺治疗脑出血患者的研究（i-DEF）：一项多中心、随机、安慰剂对照、双盲的 2 期临床试验。
Lancet Neurol. 2019 May;18(5):428-438. doi: 10.1016/S1474-4422(19)30069-9. Epub 2019 Mar 18.
7
Is asymptomatic hemorrhagic transformation really innocuous?无症状性出血性转化真的无害吗？
Neurology. 2012 Feb 7;78(6):421-6. doi: 10.1212/WNL.0b013e318245d22c. Epub 2012 Jan 25.
8
Iron mediates endothelial cell damage and blood-brain barrier opening in the hippocampus after transient forebrain ischemia in rats.铁介导大鼠短暂前脑缺血后海马内皮细胞损伤和血脑屏障开放。
Exp Mol Med. 2011 Feb 28;43(2):121-8. doi: 10.3858/emm.2011.43.2.020.
9
Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke Trial.无症状性梗死出血转化及其与功能结局和卒中亚型的关系：来自替奈普酶治疗急性缺血性卒中试验的评估。
Stroke. 2010 Dec;41(12):2834-9. doi: 10.1161/STROKEAHA.109.573063. Epub 2010 Oct 28.
10
Effects of deferoxamine on brain injury after transient focal cerebral ischemia in rats with hyperglycemia.去铁胺对高血糖大鼠短暂性局灶性脑缺血后脑损伤的影响
Brain Res. 2009 Sep 29;1291:113-21. doi: 10.1016/j.brainres.2009.07.032. Epub 2009 Jul 23.