Clermont Auvergne University, EA 3533, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), CRNH Auvergne, Clermont-Ferrand63000, France.
International Research Chair Health in Motion, Clermont Auvergne University Foundation, Clermont-Ferrand, France.
Br J Nutr. 2024 Jan 28;131(2):359-368. doi: 10.1017/S0007114523001824. Epub 2023 Aug 17.
Recent evidence suggests better appetite control in states of high-energy flux (HEF) in adults and lean children. Nevertheless, it is unknown whether this extends to youth with obesity. This study compares the effects of low, moderate or HEF on short-term appetitive control in adolescents with obesity. Sixteen adolescents with obesity (12-16 years, Tanner stages 3-5, 11 females) randomly completed three conditions: (i) low-energy flux (LEF); (ii) moderate energy flux (MEF; + 250 kcal) and (iii) HEF (HEF; + 500 kcal). Energy flux was achieved in MEF and HEF through elevated energy intake (EI) and concomitant increase in energy expenditure using cycling exercise (65 % VO). EI, macronutrient intake and relative EI were assessed at dinner, subjective appetite sensations taken at regular intervals and food reward measured before dinner. EI at dinner was greater in LEF compared with HEF ( = 0·008), and relative EI (REI) was higher in LEF compared with MEF ( = 0·003) and HEF ( < 0·001). The absolute consumption of carbohydrates was lower in LEF compared with MEF ( = 0·047) and HEF ( < 0·001). Total AUC for hunger and desire to eat was lower in HEF compared with LEF ( < 0·001) and MEF ( = 0·038). Total AUC for prospective food consumption was lower on HEF compared with LEF ( = 0·004). Food choice sweet bias was higher in HEF ( = 0·005) compared with LEF. To conclude, increasing energy flux may improve short-term appetite control in adolescents with obesity.
最近的证据表明，在成年人和瘦儿童的高能通量（HEF）状态下，食欲控制更好。然而，目前尚不清楚这是否适用于肥胖的青少年。本研究比较了低、中或 HEF 对肥胖青少年短期食欲控制的影响。16 名肥胖青少年（12-16 岁，Tanner 阶段 3-5，11 名女性）随机完成了三种条件：（i）低能量通量（LEF）；（ii）中等能量通量（MEF；+250 千卡）和（iii）高能通量（HEF；+500 千卡）。MEF 和 HEF 中的能量通量通过提高能量摄入（EI）和使用循环运动（65%VO）相应增加能量消耗来实现。EI、宏量营养素摄入量和相对 EI 在晚餐时进行评估，定期测量主观食欲感觉，并在晚餐前测量食物奖励。与 HEF 相比，LEF 时晚餐时 EI 更高（=0.008），与 MEF 和 HEF 相比，LEF 时相对 EI（REI）更高（=0.003 和<0.001）。与 MEF 和 HEF 相比，LEF 时碳水化合物的绝对摄入量较低（=0.047 和<0.001）。与 LEF 和 MEF 相比，HEF 时饥饿和进食欲望的总 AUC 较低（<0.001 和=0.038）。与 LEF 相比，HEF 时预期食物摄入量的总 AUC 较低（=0.004）。HEF 时的食物选择甜食偏好较高（=0.005）与 LEF 相比。总之，增加能量通量可能会改善肥胖青少年的短期食欲控制。
