Chopra V K, Mohanan P P, Kher Vijay, Mantri Raja Ram, Isaacs Rajan, Jadhav Uday, Zalte Nitin, Sugumaran Amarnath, Mohanasundaram Senthilnathan
Clinical Cardiology Heart Failure and Research, Max Super Speciality Hospital, New Delhi, IND.
Cardiology, Westfort Hi-Tech Hospital, Thrissur, IND.
Cureus. 2023 Jul 16;15(7):e41957. doi: 10.7759/cureus.41957. eCollection 2023 Jul.
Heart failure is associated with an increased frequency of hospitalization, reduced life span, and greater risk to public health, thus posing a challenge. In India, torsemide is one of the commonly used loop diuretics for decongestion in heart failure. However, this use of torsemide, including its dosing, and up/down titration, is based on practical experience. Loop diuretic therapy for heart failure patients poses several dilemmas due to the lack of robust evidence based on which treatment decisions can be made. To guide physicians on the optimal use of torsemide in heart failure patients with or without renal impairment, a panel of expert cardiologists and nephrologists from India convened to develop this expert opinion document for the use of torsemide. This expert opinion on torsemide will pave the way for optimal management with loop diuretic therapy in real-world heart failure patients.
心力衰竭与住院频率增加、寿命缩短以及对公众健康的更大风险相关，因此构成了一项挑战。在印度，托拉塞米是心力衰竭时常用的袢利尿剂之一，用于减轻充血。然而，托拉塞米的这种使用，包括其剂量以及上调/下调滴定，都是基于实践经验。由于缺乏可据此做出治疗决策的有力证据，心力衰竭患者的袢利尿剂治疗存在若干困境。为了指导医生在有或无肾功能损害的心力衰竭患者中最佳使用托拉塞米，来自印度的一组心脏病专家和肾病专家组成的小组召开会议，制定了这份关于托拉塞米使用的专家意见文件。这份关于托拉塞米的专家意见将为现实世界中心力衰竭患者的袢利尿剂最佳管理铺平道路。
