Kumar Hansraj, Sudha Sty, Kumar Subodh, A Harminder Singh
Department of Pharmacology, All India Institute of Medical Sciences, Deoghar-814142, India.
Maedica (Bucur). 2023 Jun;18(2):373-375. doi: 10.26574/maedica.2023.18.2.373.
Eyelid dermatitis is a common occurrence in several skin disorders, including seborrheic dermatitis, atopic dermatitis and psoriasis. However, it is primarily associated with allergic contact dermatitis (ACD). Here, we present a case of 51-year-old woman who developed pruritic erythema of the eyelids after using 0.1% Nepafenac eye drops. Nepafenac is a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed as eye drops for various inflammatory eye conditions. Instances of ACD caused by Nepafenac eye drops are exceedingly rare based on available case reports. Nevertheless, it is important to consider ACD as a potential cause when a patient with eyelid dermatitis has a history of Nepafenac eye drop usage. The Naranjo algorithm, which was used for assessing causality, determined the likelihood of this case being a possible instance of ACD due to Nepafenac (Naranjo score=3).
眼睑皮炎在多种皮肤疾病中较为常见，包括脂溢性皮炎、特应性皮炎和银屑病。然而，它主要与过敏性接触性皮炎（ACD）相关。在此，我们报告一例51岁女性病例，该患者在使用0.1%那法根滴眼液后出现眼睑瘙痒性红斑。那法根是一种非甾体抗炎药（NSAID），通常作为滴眼液用于治疗各种炎症性眼部疾病。根据现有病例报告，那法根滴眼液引起的ACD病例极为罕见。尽管如此，当患有眼睑皮炎的患者有使用那法根滴眼液的病史时，将ACD视为潜在病因很重要。用于评估因果关系的Naranjo算法确定该病例有可能是由那法根引起的ACD（Naranjo评分为3）。
