el Zayadi A, Khalil A, el Samny N, Hamza M R, Selim O
Hepatogastroenterology. 1986 Aug;33(4):148-50.
A greatly increased incidence of hepatic angiosarcoma (H.A.S.) among Egyptian farmers involved in pest-control spraying operations attracted our attention. Fourteen patients were diagnosed at Ain Shams University Hospital between the years 1980-1984 as having H.A.S. Eleven were males and 3 females with an average age of 49 years, and a male:female ratio of 3.8:1. Eleven patients reside in Lower Egypt and 3 in Upper Egypt. Ten out of the 14 patients had a definite history of a direct chronic recurrent exposure to agricultural pesticides of variable chemical nature, throughout the year. The period of exposure ranged from 11-20 years with an average of 14 years. The other 4 patients had no history of exposure to any of the known carcinogenic factors. This significant increase in angiosarcoma among farmers involved in pesticide spraying suggests that agricultural pesticides might play a role in the genesis of H.A.S. in Egypt.
参与害虫防治喷洒作业的埃及农民中，肝血管肉瘤（H.A.S.）的发病率大幅上升，这引起了我们的关注。1980年至1984年间，艾因夏姆斯大学医院诊断出14例患有H.A.S.的患者。其中11例为男性，3例为女性，平均年龄49岁，男女比例为3.8:1。11名患者居住在下埃及，3名居住在上埃及。14名患者中有10名全年都有明确的直接慢性反复接触各种化学性质农药的病史。接触时间为11至20年，平均14年。其他4名患者没有接触任何已知致癌因素的病史。参与农药喷洒的农民中血管肉瘤的显著增加表明，农用农药可能在埃及H.A.S.的发生中起作用。
