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神经内镜:儿童脑室和颅底肿瘤切除术。

Neuroendoscopy: intraventricular and skull base tumor resection in children.

机构信息

Department of Neurosurgery, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.

Department of Neurosurgery, Bombay Hospital, Mumbai, India.

出版信息

Childs Nerv Syst. 2023 Oct;39(10):2737-2756. doi: 10.1007/s00381-023-06110-z. Epub 2023 Aug 17.

Abstract

During the last 30 years, the neurosurgeons have witnessed a revolution in the practice of interventricular surgery. The advent of neuroendoscopy at the end of the 1980s has allowed a minimally invasive management of a very large series of pathologies in pediatric neurosurgery ranging from hydrocephalus to arachnoid cyst to intraventricular tumors. The progresses in the management of hydrocephalus, intracranial cyst, and the fluid filled collection nevertheless has been more rapid and radical due to the simpler equipment that is necessary to perform this kind of surgery. The intraventricular tumors instead have been addressed in a slower way, and for many years, the only endoscopic procedure that was allowed on interventricular tumors was a biopsy associated with the management of hydrocephalus. Only very small tumors have been considered operable for complete removal during many years due to the limitations of the neuroendoscopic equipment and to the small calibers of the working channel. More recently, the advent of new devices and new surgical techniques are offering new perspectives on the possibility of intraventricular tumor surgery in children. In this review, we describe the historical perspective of the learning curve of intraventricular tumor surgery under neuroendoscopic control and try to offer a view of the future perspective in the removal of larger intraventricular tumors, analyzing the main indications for intraventricular endoscopic tumor surgery. We offer as well an historical perspective of the evolution of skull base surgery and endonasal transsphenoidal approach for skull-based tumors in children. This kind of surgery that has acquired widespread acceptance for many pathologies in adult age has diffused more slowly in pediatric neurosurgery due to the anatomical limitation observed in these age range. Also in this field, the slow evolution of the technique and of the technology available to neurosurgeons has allowed a very significant expansion of indication for the minimally invasive removal of skull base tumors in children.

摘要

在过去的 30 年中,神经外科医生见证了脑室手术实践的革命。20 世纪 80 年代末神经内镜的出现,使得小儿神经外科的一系列非常大的病理学可以通过微创管理,从脑积水到蛛网膜囊肿到脑室内肿瘤。尽管由于执行此类手术所需的设备更简单,但脑积水、颅内囊肿和充满液体的收集物的管理进展更快、更彻底。脑室内肿瘤的处理方式则较为缓慢,多年来,允许在脑室内肿瘤上进行的唯一内镜手术是与脑积水管理相关的活检。由于神经内镜设备的限制和工作通道的小口径,多年来,只有非常小的肿瘤被认为可以通过完全切除来治疗。最近,新设备和新技术的出现为儿童脑室内肿瘤手术提供了新的可能性。在这篇综述中,我们描述了在神经内镜控制下进行脑室内肿瘤手术的学习曲线的历史发展,并试图对更大的脑室内肿瘤切除的未来前景进行展望,分析脑室内内镜肿瘤手术的主要适应证。我们还对颅底手术和儿童颅底肿瘤经鼻蝶入路的历史发展进行了分析。这种在成人许多疾病中得到广泛认可的手术,由于在这些年龄段观察到的解剖学限制,在小儿神经外科中的传播速度较慢。在这个领域,技术和技术的缓慢发展也使得微创切除儿童颅底肿瘤的适应证得到了极大的扩展。

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