Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong.
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, South Korea.
Otol Neurotol. 2023 Oct 1;44(9):912-917. doi: 10.1097/MAO.0000000000003996. Epub 2023 Aug 15.
The implementation of nonpharmaceutical interventions (NPIs) for coronavirus disease 2019 (COVID-19) may affect the incidence of infectious diseases. This study aimed to evaluate the changes in the incidence of pediatric acute otitis media (AOM) after the COVID-19 outbreak in Seoul, South Korea.
Retrospective cohort.
Tertiary referral center.
We ascertained the daily number of COVID-19 and pediatric AOM patients between January 20, 2020, and June 19, 2020. During the same period, the number of children using public transportation was used as an index for implementing NPIs. The same period 1 year ago was set as the control period.
Diagnostic.
The differences in the incidence of AOM and implementation of NPIs between the COVID-19 pandemic and control period were analyzed using segmented regression analyses. Negative values of difference meant that the number in the COVID-19 pandemic period declined compared with the control period.
The study period was divided into two sections based on the change point of the COVID-19 cases. In the first period, the increased number of COVID-19 cases decreased, and in the second period, the number of COVID-19 cases increased again. Similar trends were observed in the incidence of AOM and NPI implementation. Before the change point, the study found a significant decreasing trend in the differences in pediatric AOM cases and children using public transportation. However, these trends changed after the change point, with a significant increase in both indices.
Our findings indicate that NPIs for COVID-19 may influence the incidence of pediatric AOM.
实施针对 2019 年冠状病毒病(COVID-19)的非药物干预措施(NPIs)可能会影响传染病的发病率。本研究旨在评估韩国首尔 COVID-19 爆发后小儿急性中耳炎(AOM)发病率的变化。
回顾性队列研究。
三级转诊中心。
我们确定了 2020 年 1 月 20 日至 2020 年 6 月 19 日期间 COVID-19 和小儿 AOM 患者的每日数量。在此期间,使用儿童使用公共交通工具的数量作为实施 NPIs 的指标。同期前一年设为对照组。
诊断。
使用分段回归分析比较 COVID-19 大流行和对照期间 AOM 发病率和 NPIs 实施的差异。差异的负值意味着与对照期间相比,COVID-19 流行期间的数量减少。
根据 COVID-19 病例的变化点将研究期间分为两段。在第一阶段,COVID-19 病例的增加数量减少,而在第二阶段,COVID-19 病例再次增加。AOM 发病率和 NPI 实施也呈现出类似的趋势。在变化点之前,研究发现小儿 AOM 病例和使用公共交通工具的儿童数量差异呈显著下降趋势。然而,这些趋势在变化点后发生了变化,两个指标均显著增加。
我们的研究结果表明,COVID-19 的 NPIs 可能会影响小儿 AOM 的发病率。