Al Ozairi Ebaa, ElSamad Abeer, Al Kandari Jumana, Hamdan Yasmine, Taliping Dennis, Gray Stuart R
Clinical Research Unit, Dasman Diabetes Institute, Kuwait; Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait.
Clinical Research Unit, Dasman Diabetes Institute, Kuwait.
Diabetes Metab Syndr. 2023 Sep;17(9):102845. doi: 10.1016/j.dsx.2023.102845. Epub 2023 Aug 11.
The aim of the current study was to compare glucose responses when remotely supervised exercise was performed before or after breaking the fast, during Ramadan, in people with type 1 diabetes.
People with type 1 diabetes were recruited to this randomised cross over design study, which took place in Kuwait during Ramadan in 2021-2022. Interstitial glucose was measured using continuous glucose monitors during a baseline week of normal activity and during weeks where remotely supervised exercise was performed, three times per week, either before (afternoon) or after (evening) breaking the fast, in a randomised crossover design. Exercise involved resistance and aerobic exercise and was supervised during a video call.
Thirty-two participants were recruited to the study (age 34(9) years and BMI 26(4)kg/m). Mean interstitial glucose levels were lower on exercise days, compared to equivalent days in the baseline week, during both afternoon (8.6(1.8) mmol/L vs 9.1(1.4) mmol/L, p = 0.035) and evening (8.7(1.8) mmol/L vs 9.6(1.8) mmol/L, p < 0.001) exercise weeks. Mean glucose levels were lower the day after exercise, relative to both baseline (p < 0.001) and exercise (p = 0.011) days, in the evening exercise week only.
Remotely supervised exercise performed during Ramadan can safely reduce interstitial glucose levels and may be of greater benefit when performed in the evening, further work is required to confirm this in a larger trial.
本研究旨在比较1型糖尿病患者在斋月期间禁食前后进行远程监督运动时的血糖反应。
招募1型糖尿病患者参加这项随机交叉设计研究，该研究于2021 - 2022年斋月期间在科威特进行。在正常活动的基线周以及进行远程监督运动的几周内，使用连续血糖监测仪测量组织间液葡萄糖水平，运动为每周三次，采用随机交叉设计，分别在禁食前（下午）或禁食后（晚上）进行。运动包括抗阻运动和有氧运动，并通过视频通话进行监督。
32名参与者被纳入研究（年龄34（9）岁，体重指数26（4）kg/m²）。在下午（8.6（1.8）mmol/L对9.1（1.4）mmol/L，p = 0.035）和晚上（8.7（1.8）mmol/L对9.6（1.8）mmol/L，p < 0.001）运动周期间，与基线周的相应日子相比，运动日的平均组织间液葡萄糖水平较低。仅在晚上运动周，运动后一天的平均血糖水平相对于基线日（p < 0.001）和运动日（p = 0.011）均较低。
斋月期间进行的远程监督运动可安全降低组织间液葡萄糖水平，晚上进行可能更有益，需要进一步开展更大规模试验予以证实。
