Elmusa Emad, Raza Muhammad Waleed, Muneeb Ahmad, Zahoor Hovra, Naddaf Naja
Internal Medicine, Hospital Corporation of America Florida (HCA FL) Orange Park Hospital, Orange Park, USA.
Cureus. 2023 Jul 17;15(7):e42012. doi: 10.7759/cureus.42012. eCollection 2023 Jul.
Catastrophic antiphospholipid syndrome (CAPS) is a rare variant of antiphospholipid syndrome (APLS). CAPS is a syndrome characterized by microvascular thrombosis leading to multi-organ failure, including acute heart failure. Diagnosis is challenging, and disease progression is rapid. Treatment includes triple therapy with anticoagulation, glucocorticoids, and plasma exchange. We present a case of a patient with CAPS who developed de novo acute heart failure. With treatment, the patient's multi-organ failure improved, including cardiac function. It is our goal to present this case in order to facilitate greater diagnostic suspicion and the early treatment of CAPS to reduce morbidity and mortality.
灾难性抗磷脂综合征（CAPS）是抗磷脂综合征（APLS）的一种罕见变异型。CAPS是一种以微血管血栓形成导致多器官功能衰竭为特征的综合征，包括急性心力衰竭。诊断具有挑战性，且疾病进展迅速。治疗包括抗凝、糖皮质激素和血浆置换的三联疗法。我们报告一例CAPS患者发生新发急性心力衰竭的病例。经过治疗，患者的多器官功能衰竭有所改善，包括心脏功能。我们展示此病例的目的是促进对CAPS有更高的诊断怀疑并尽早治疗，以降低发病率和死亡率。
