胰凝乳蛋白酶催化荧光氨基酸酰胺和肽衍生物的合成。
Chymotrypsin catalysed synthesis of fluorescent amino acid amide and peptide derivatives.
作者信息
Skalli A, Pugnière M, Coletti-Previero M A, Torreilles J, Previero A
出版信息
Int J Pept Protein Res. 1986 Jul;28(1):1-5. doi: 10.1111/j.1399-3011.1986.tb03223.x.
Abstract
Chymotrypsin catalyses a condensation reaction between 1-methyl-3,4-dihydro-beta-carboline-3-methyl carboxylate and amino acid amides or peptides, yielding fluorescent derivatives. During the peptide bond formation, the enzyme ensures the reaction's steric control of both carboxyl and amino components.
摘要
胰凝乳蛋白酶催化1-甲基-3,4-二氢-β-咔啉-3-甲基羧酸酯与氨基酸酰胺或肽之间的缩合反应，生成荧光衍生物。在肽键形成过程中，该酶确保反应对羧基和氨基成分的空间控制。
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