Montgomery R D, Pidgeon G L
J Am Vet Med Assoc. 1986 Sep 15;189(6):684-5.
A single oral dose of levamisole hydrochloride given at the rate of 12 mg/kg was believed responsible for bradycardia, tachypnea, hypothermia, cerebrocortical depression, and diarrhea in a dog. Supportive treatment and symptomatic treatment for the bradycardia were required for 4 days. In addition to these previously reported abnormalities associated with levamisole toxicosis, cerebrocortical depression and multiple foci of irritation were characterized by electroencephalography.
据信,以12毫克/千克的剂量单次口服盐酸左旋咪唑导致了一只狗出现心动过缓、呼吸急促、体温过低、大脑皮质抑制和腹泻。心动过缓需要进行4天的支持性治疗和对症治疗。除了这些先前报道的与左旋咪唑中毒相关的异常情况外,脑电图显示存在大脑皮质抑制和多个刺激灶。