Spyridakis L, Brown S, Barsanti J, Hardie E M, Carlton B
J Am Vet Med Assoc. 1986 Sep 15;189(6):690-1.
A dog with hypoalbuminemia, proteinuria, and renal amyloidosis was treated with dimethylsulfoxide for 2 years. During a 1-year period, serum albumin concentrations increased to within normal range. The 24-hour urinary protein excretion was 5.7 g before treatment with dimethylsulfoxide. Two years after initiation of treatment, the 24-hour urinary protein excretion was 3.7 g. Removal of a testicle containing a Sertoli cell tumor and treatment of interdigital pyoderma may have been factors in the dog's clinical improvement. The only adverse effect from the dimethylsulfoxide treatment was the characteristic disagreeable odor.
一只患有低白蛋白血症、蛋白尿和肾淀粉样变性的狗用二甲亚砜治疗了2年。在1年的时间里，血清白蛋白浓度升至正常范围。在用二甲亚砜治疗前，24小时尿蛋白排泄量为5.7克。开始治疗两年后，24小时尿蛋白排泄量为3.7克。切除一个含有支持细胞瘤的睾丸以及治疗指间脓皮病可能是这只狗临床症状改善的因素。二甲亚砜治疗唯一的不良反应是特有的难闻气味。
