Bravo-Taxa Mercedes, Berrospi-Espinoza Francisco, Taxa-Rojas Luis
Departamento de Patología; Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima, Perú; Departamento de Patología; Laboratorio Oncológico Taxa (LOT), Lima, Perú.
Departamento de Cirugía Digestiva; Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima, Perú; Departamento de Cirugía; Clínica Detecta, Lima, Perú.
Rev Gastroenterol Peru. 2023 Apr-Jun;43(2):161-165.
Pancreatic hamartomas (PH) are extremely unusual non-neoplastic tumor-like lesions and accounts for <1% of all hamartomas. Moreover, there is a distinct variant of PH denominated Pancreatic lipomatous hamartoma (PLH), that is even rarer, with only 5 cases, including the present case, reported in the literature. PLH lacks well-defined features and clinically can be mistaken with other lipomatous lesions of the pancreas, including lipoma, pancreatic lipomatosis, PEComa, liposarcoma, and malignant tumors with lipomatous components. Here, we describe a case of PLH in a 70-year-old male with abdominal pain and a lesion, which was preoperatively diagnosed as a pancreatic no functional low-grade neuroendocrine tumor, and subsequent underwent a laparoscopic enucleation of the tumor. The postoperative pathology and immunohistochemical analyses confirmed the diagnosis of PLH.
胰腺错构瘤(PH)是极其罕见的非肿瘤性肿瘤样病变,占所有错构瘤的比例不到1%。此外,有一种独特的PH变异型,称为胰腺脂肪瘤样错构瘤(PLH),更为罕见,文献中仅报道了5例,包括本病例。PLH缺乏明确的特征,临床上可能与胰腺的其他脂肪瘤样病变混淆,包括脂肪瘤、胰腺脂肪过多症、PEComa、脂肪肉瘤以及具有脂肪瘤成分的恶性肿瘤。在此,我们描述一例70岁男性的PLH病例,该患者有腹痛且存在一个病变,术前被诊断为胰腺无功能低级别神经内分泌肿瘤,随后接受了肿瘤的腹腔镜摘除术。术后病理及免疫组化分析确诊为PLH。