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低位天幕和上半规管裂修补术后中颅窝的手术结果。

Low-Lying Tegmen and Surgical Outcomes Following the Middle Cranial Fossa Repair of Superior Canal Dehiscence.

机构信息

Department of Head and Neck Surgery, David Geffen School of Medicine at University of California, Los Angeles, California, USA.

Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, California, USA.

出版信息

Otolaryngol Head Neck Surg. 2024 Jan;170(1):195-203. doi: 10.1002/ohn.480. Epub 2023 Aug 20.

Abstract

OBJECTIVE

To compare treatment response from the middle cranial fossa repair of superior canal dehiscence (SCD) between cases with and cases without low-lying tegmen (LLT).

STUDY DESIGN

Cohort study.

SETTING

Single tertiary care institution.

METHODS

Two investigators independently reviewed preoperative high-resolution temporal bone computed tomography images and classified the ipsilateral tegmen as either "low-lying" or "control." Patients completed a symptom questionnaire and underwent audiometric testing pre- and post-operatively. Multivariable regression models assessed for symptomatic resolution and audiometric improvement following surgery with tegmen status as the primary predictor. Models controlled for patient age, sex, bilateral SCD disease, dehiscence location, prior ear surgery status, surgery duration, and follow-up duration.

RESULTS

Among a total of 410 cases included, we identified 121 (29.5%) LLT cases. Accounting for all control measures, patients with LLT were significantly less likely to experience overall symptom improvement (adjusted odds ratio: 0.32, 95% confidence interval [CI]: 0.18-0.57, p < .001) and reported a significantly lower proportion of preoperative symptoms that resolved following surgery (adjusted β: -25.6%, 95% CI: -37.0% to -14.3%, p < .001). However, audiometric outcomes following surgery did not differ significantly between patients with and patients without LLT.

CONCLUSION

This is the first investigation on the relationship between LLT and surgical outcomes following the middle fossa repair of SCD. Patients with LLT reported less favorable symptomatic response but exhibited a similar degree of audiometric improvement.

摘要

目的

比较颅中窝修复上半规管裂(SCD)中伴有和不伴有低位天幕(LLT)的病例的治疗反应。

研究设计

队列研究。

设置

单一的三级保健机构。

方法

两名调查员独立审查术前高分辨率颞骨计算机断层扫描图像,并将同侧天幕分为“低位”或“对照”。患者在术前和术后完成症状问卷并接受听力测试。多变量回归模型评估伴有或不伴有天幕状态的手术治疗后症状缓解和听力改善情况,天幕状态为主要预测因子。模型控制了患者年龄、性别、双侧 SCD 疾病、裂孔位置、既往耳部手术史、手术持续时间和随访时间。

结果

在总共 410 例病例中,我们发现了 121 例(29.5%)LLT 病例。考虑到所有的对照措施,LLT 患者的总体症状改善的可能性明显降低(调整后的优势比:0.32,95%置信区间 [CI]:0.18-0.57,p<0.001),并且术后报告的术前症状缓解比例明显降低(调整后的β:-25.6%,95% CI:-37.0%至-14.3%,p<0.001)。然而,手术后的听力结果在伴有和不伴有 LLT 的患者之间没有显著差异。

结论

这是首次调查低位天幕与颅中窝修复 SCD 术后手术结果之间的关系。伴有 LLT 的患者报告的症状反应较差,但听力改善程度相似。

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