骨桥蛋白水平与糖尿病早期糖尿病心肌病的严重程度相关。
Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes.
机构信息
First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.
Department of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
出版信息
Diabetes Res Clin Pract. 2023 Sep;203:110885. doi: 10.1016/j.diabres.2023.110885. Epub 2023 Aug 19.
Diabetic cardiomyopathy (DbCM) is characterized by restrictive pattern and consistent risk of overt heart failure. We here focused osteopontin (OPN), which was tested independently associated with left ventricular diastolic dysfunction (LVDD). Overall, OPN increased with DbCM severity according with the presence of left atrial dilatation, LV hypertrophy and LVDD.
糖尿病心肌病（DbCM）的特征是限制性模式和明显心力衰竭的一致风险。我们在这里重点研究了骨桥蛋白（OPN），它被独立测试与左心室舒张功能障碍（LVDD）相关。总的来说，随着 DbCM 严重程度的增加，OPN 增加，同时伴有左心房扩张、左室肥厚和 LVDD。
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