Hofstetter J R, Ebiner J R
Schweiz Med Wochenschr. 1979 Jun 23;109(25):934-7.
The symptoms of cirrhosis are inconsistent and appear late in the course of the disease. Laboratory tests are also of variable value; generally speaking, cytolysis is observed infrequently. The gamma-GT test is the most sensitive in alcoholic cirrhosis, but may be more an expression of the degree of alcoholism than of the hepatic lesion per se. In cirrhosis, the best diagnostic method is a combination of laparoscopy and puncture biopsy. Endoscopy permits diagnosis not only of the hepatic lesion but also of the complications which may ensure, such as portal hypertension and ascites. Alcoholic abstinence appears to improve the prognosis of alcoholic cirrhosis. The prognosis in this condition may, in fact, be better than has been suspected.
肝硬化的症状并不一致,且在疾病进程后期才出现。实验室检查的价值也各不相同;一般来说,很少观察到细胞溶解现象。γ-谷氨酰转肽酶检测在酒精性肝硬化中最为敏感,但它可能更多地是酒精中毒程度的一种表现,而非肝脏病变本身的体现。对于肝硬化,最佳诊断方法是腹腔镜检查和穿刺活检相结合。内镜检查不仅可以诊断肝脏病变,还能诊断可能随之出现的并发症,如门静脉高压和腹水。戒酒似乎能改善酒精性肝硬化的预后。实际上,这种情况下的预后可能比人们预想的要好。