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[肝硬变门静脉高压症的预后(作者译)]

[Prognosis of portal hypertension in hepatitic cirrhosis of the liver (author's transl)].

作者信息

Mörl M, Gehring D, Wannagat L

出版信息

Dtsch Med Wochenschr. 1981 Jul 31;106(31-32):990-3. doi: 10.1055/s-2008-1070440.

Abstract

Laparoscopic transhepatic measurement of pressures in the branches of the portal vein (and hepatic vein) were performed in 42 patients with hepatitic cirrhosis of the liver and compared with those obtained in patients with other defined causes of cirrhosis (alcohol, pigment, Budd-Chiari syndrome, right heart failure). Mean portal vein pressure was 27.2, mean hepatic vein pressure 14.5 mm Hg. A significant pressure difference (Kruskal-Wallis test) was present only between hepatitic cirrhosis and congestive cirrhosis, not alcohol or pigment cirrhosis. During the period of observation (1975-1978) there was a high incidence of deaths and complications in the hepatitic group compared with other forms of cirrhosis: 6 treatment-resistant and 2 successfully treated cases of bleeding from oesophageal varices. The risk of bleeding begins at a pressure above 27 mm Hg, but in individual cases it cannot be used to prognosticate.

摘要

对42例肝硬化患者进行了腹腔镜经肝门静脉(及肝静脉)分支压力测量,并与其他明确病因的肝硬化患者(酒精性、色素性、布加综合征、右心衰竭)进行比较。门静脉平均压力为27.2,肝静脉平均压力为14.5 mmHg。仅在肝炎后肝硬化和充血性肝硬化之间存在显著压力差异(Kruskal-Wallis检验),酒精性或色素性肝硬化则无。在观察期(1975 - 1978年),与其他形式的肝硬化相比,肝炎组的死亡和并发症发生率较高:6例食管静脉曲张出血治疗无效,2例治疗成功。出血风险始于压力高于27 mmHg,但在个别病例中不能用于预后判断。

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