Pavicic Mirko, Walker Angelica M, Sullivan Kyle A, Lagergren John, Cliff Ashley, Romero Jonathon, Streich Jared, Garvin Michael R, Pestian John, McMahon Benjamin, Oslin David W, Beckham Jean C, Kimbrel Nathan A, Jacobson Daniel A
Oak Ridge National Laboratory, Computational and Predictive Biology, Oak Ridge, TN, United States.
The Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee Knoxville, Knoxville, TN, United States.
Front Psychiatry. 2023 Aug 1;14:1178633. doi: 10.3389/fpsyt.2023.1178633. eCollection 2023.
Despite a recent global decrease in suicide rates, death by suicide has increased in the United States. It is therefore imperative to identify the risk factors associated with suicide attempts to combat this growing epidemic. In this study, we aim to identify potential risk factors of suicide attempt using geospatial features in an Artificial intelligence framework.
We use iterative Random Forest, an explainable artificial intelligence method, to predict suicide attempts using data from the Million Veteran Program. This cohort incorporated 405,540 patients with 391,409 controls and 14,131 attempts. Our predictive model incorporates multiple climatic features at ZIP-code-level geospatial resolution. We additionally consider demographic features from the American Community Survey as well as the number of firearms and alcohol vendors per 10,000 people to assess the contributions of proximal environment, access to means, and restraint decrease to suicide attempts. In total 1,784 features were included in the predictive model.
Our results show that geographic areas with higher concentrations of married males living with spouses are predictive of lower rates of suicide attempts, whereas geographic areas where males are more likely to live alone and to rent housing are predictive of higher rates of suicide attempts. We also identified climatic features that were associated with suicide attempt risk by age group. Additionally, we observed that firearms and alcohol vendors were associated with increased risk for suicide attempts irrespective of the age group examined, but that their effects were small in comparison to the top features.
Taken together, our findings highlight the importance of social determinants and environmental factors in understanding suicide risk among veterans.
尽管近期全球自杀率有所下降,但美国的自杀死亡人数却有所增加。因此,识别与自杀未遂相关的风险因素对于应对这一日益严重的流行病至关重要。在本研究中,我们旨在利用人工智能框架中的地理空间特征来识别自杀未遂的潜在风险因素。
我们使用可解释的人工智能方法——迭代随机森林,利用百万退伍军人计划的数据来预测自杀未遂情况。该队列纳入了405,540名患者,其中有391,409名对照者和14,131次自杀未遂事件。我们的预测模型纳入了邮政编码级地理空间分辨率下的多个气候特征。我们还考虑了美国社区调查中的人口统计学特征以及每万人中的枪支和酒精销售商数量,以评估近端环境、获取手段和抑制因素减少对自杀未遂的影响。预测模型总共纳入了1,784个特征。
我们的结果表明,已婚男性与配偶同住比例较高的地理区域自杀未遂率较低,而男性更有可能独自居住和租房的地理区域自杀未遂率较高。我们还确定了按年龄组划分的与自杀未遂风险相关的气候特征。此外,我们观察到,无论所研究的年龄组如何,枪支和酒精销售商都与自杀未遂风险增加有关,但与首要特征相比,它们的影响较小。
综上所述,我们的研究结果凸显了社会决定因素和环境因素在理解退伍军人自杀风险方面的重要性。