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4DCT对甲状旁腺腺瘤的鉴别诊断:一例报告

4DCT Differentiation of Parathyroid Adenoma: A Case Report.

作者信息

Mwewa Tana Bupe, Raeymaeckers Steven

机构信息

UZ Brussel, Belgium.

出版信息

J Belg Soc Radiol. 2023 Aug 17;107(1):61. doi: 10.5334/jbsr.3238. eCollection 2023.

DOI:10.5334/jbsr.3238
PMID:37600564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10437132/
Abstract

UNLABELLED

We report the case of a 72-year-old patient presenting with recurrent primary hyperparathyroidism after total thyroidectomy and parathyroidectomy with presternal autotransplantation. Methionine-PET-CT proved false-positive and Tc-99m-tetrofosmine imaging false-negative. Using a novel multiphase-4DCT technique we identified an anterior mediastinal nodule demonstrating contrast wash-in and wash-out, suggesting parathyroid adenoma. Traditional 4DCT-protocols obtain fewer phases; therefore, this enhancement pattern might have gone unnoticed. After surgical resection the bloodwork normalized, histopathology confirmed a parathyroid adenoma.

TEACHING POINT

Multiphase 4DCT is a potentially helpful technique for the detection of parathyroid adenomas after total thyroidectomy and parathyroidectomy.

摘要

未标注

我们报告了一例72岁患者,在全甲状腺切除和甲状旁腺切除并行胸骨前自体移植后出现复发性原发性甲状旁腺功能亢进。蛋氨酸PET-CT结果为假阳性,锝-99m替曲膦显像结果为假阴性。使用一种新型的多期4DCT技术,我们发现了一个前纵隔结节,该结节显示有造影剂流入和流出,提示为甲状旁腺腺瘤。传统的4DCT协议获得的期数较少;因此,这种强化模式可能未被注意到。手术切除后血液检查恢复正常,组织病理学证实为甲状旁腺腺瘤。

教学要点

多期4DCT是全甲状腺切除和甲状旁腺切除术后检测甲状旁腺腺瘤的一种潜在有用技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/e2c2148497e8/jbsr-107-1-3238-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/aa9c814a7622/jbsr-107-1-3238-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/eda2ace85b37/jbsr-107-1-3238-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/e2c2148497e8/jbsr-107-1-3238-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/aa9c814a7622/jbsr-107-1-3238-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/eda2ace85b37/jbsr-107-1-3238-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b18/10437132/e2c2148497e8/jbsr-107-1-3238-g3.jpg

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本文引用的文献

1
4DCT Scanning Technique for Primary Hyperparathyroidism: A Scoping Review.原发性甲状旁腺功能亢进症的4DCT扫描技术:一项范围综述
Radiol Res Pract. 2021 May 21;2021:6614406. doi: 10.1155/2021/6614406. eCollection 2021.
2
Detection of parathyroid adenomas with multiphase 4DCT: towards a true four-dimensional technique.多期相 4DCT 检测甲状旁腺腺瘤:向真正的四维技术迈进。
BMC Med Imaging. 2021 Apr 7;21(1):64. doi: 10.1186/s12880-021-00597-1.
3
Parathyroid Adenomas and Hyperplasia on Four-dimensional CT Scans: Three Patterns of Enhancement Relative to the Thyroid Gland Justify a Three-Phase Protocol.
四维 CT 扫描中的甲状旁腺腺瘤和增生:相对于甲状腺的三种增强模式证明了三相方案的合理性。
Radiology. 2015 Nov;277(2):454-62. doi: 10.1148/radiol.2015142393. Epub 2015 May 29.
4
The surgical management of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop.无症状原发性甲状旁腺功能亢进的手术治疗:第四届国际研讨会论文集。
J Clin Endocrinol Metab. 2014 Oct;99(10):3595-606. doi: 10.1210/jc.2014-2000. Epub 2014 Aug 27.
5
Current issues in the presentation of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop.无症状原发性甲状旁腺功能亢进症的当前问题:第四届国际研讨会会议记录
J Clin Endocrinol Metab. 2014 Oct;99(10):3580-94. doi: 10.1210/jc.2014-1415. Epub 2014 Aug 27.
6
Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop.无症状原发性甲状旁腺功能亢进症管理指南:第四届国际研讨会总结声明
J Clin Endocrinol Metab. 2014 Oct;99(10):3561-9. doi: 10.1210/jc.2014-1413. Epub 2014 Aug 27.
7
How to perform parathyroid 4D CT: tips and traps for technique and interpretation.如何进行甲状旁腺 4D CT:技术和解读的技巧与陷阱。
Radiology. 2014 Jan;270(1):15-24. doi: 10.1148/radiol.13122661.
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4D parathyroid CT as the initial localization study for patients with de novo primary hyperparathyroidism.4D 甲状旁腺 CT 作为新发原发性甲状旁腺功能亢进症患者的初始定位研究。
Ann Surg Oncol. 2011 Jun;18(6):1723-8. doi: 10.1245/s10434-010-1507-0. Epub 2010 Dec 24.