Fawaz Samer, Khan Sarosh, Simpson Rupert, Clesham Gerald, Cook Christopher M, Davies John R, Karamasis Grigoris V, Keeble Thomas R
Research Department, Roding Ward, Essex Cardiothoracic Centre, Mid and South Essex NHS Hospitals Trust Basildon, UK.
Department of Circulatory Health Research, Anglia Ruskin University Chelmsford, UK.
Interv Cardiol. 2023 Mar 7;18:e07. doi: 10.15420/icr.2022.30. eCollection 2023.
The landscape of interventional cardiology is ever evolving. Contemporary practice has shifted from a stenosis-centred approach to the total characterisation of both the epicardial and microcirculatory vessels. Microcirculatory dysfunction plays an important role in the pathophysiology of acute and chronic coronary syndromes, and characterisation of the microcirculation has important clinical consequences. Accordingly, the invasive diagnosis of microcirculatory dysfunction is becoming a key feature of the interventional cardiologist's toolkit. This review focuses on the methodology underpinning the invasive diagnosis of microvascular dysfunction and highlights the indices that have arisen from these methodologies.
介入心脏病学领域一直在不断发展。当代实践已从以狭窄为中心的方法转向对心外膜血管和微循环血管进行全面特征描述。微循环功能障碍在急性和慢性冠状动脉综合征的病理生理学中起重要作用，对微循环的特征描述具有重要的临床意义。因此，微循环功能障碍的有创诊断正成为介入心脏病专家工具包的一个关键特征。本综述重点关注微血管功能障碍有创诊断的基础方法，并强调从这些方法中得出的指标。
