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术前眼前节光学相干断层扫描在识别后极性白内障术中后囊膜裂开中的作用

Role of preoperative anterior segment optical coherence tomography in identifying intraoperative posterior capsular dehiscence in posterior polar cataract.

作者信息

Sarkar Shreyasi, Das Sayan

机构信息

Department of Cataract and Anterior Segment, Susrut Eye Foundation and Research Institute, Kolkata, West Bengal, India.

出版信息

Oman J Ophthalmol. 2023 Jun 27;16(2):244-251. doi: 10.4103/ojo.ojo_178_22. eCollection 2023 May-Aug.

Abstract

INTRODUCTION

The presence of preoperative posterior capsular dehiscence in posterior polar cataracts (PPCs) increases the chances of intraoperative posterior capsular rent. Our study aims to demonstrate the efficacy of preoperative anterior segment optical coherence tomography (ASOCT) to predict intraoperative posterior capsular rupture (PCR) in PPC.

MATERIALS AND METHODS

This was an observational study including patients within 25-75 years of age, having PPC, undergoing phacoemulsification. ASOCT was done for evaluating preoperative posterior capsular status and was graded as "intact" or "dehiscent, and eventually ,intraoperative-posterior capsular status was noted.

STATISTICAL ANALYSIS

SPSS (version 27.0) was used, and value of ≤ 0.05 was considered statistically significant.

RESULTS

ASOCT of 44 eyes had 9 (20.5%) dehiscent posterior capsules and 35 (79.5%) intact. Out of these 9 eyes, 7 (77.8%) had intraoperative PCR and 2 (22.2%) did not. Out of these 35, 34 (97.1%) were actually intact intraoperatively and 1 (2.9%) had intraoperative PCR. The sensitivity and specificity of ASOCT for detecting dehiscence were 94.4% and 87.5%, respectively. The positive and negative predictive values were 97.1 and 77.8, respectively. The diagnostic accuracy of the test was 95.45% with a Chi-square value of 27.01 ( < 0.0001). The diagnostic validity of ASOCT grading for detecting preoperative dehiscence was confirmed. The association between intraoperative PCR and preoperative dehiscence was statistically significant (Chi-square test - < 0.0001). Our objective was established.

DISCUSSION AND CONCLUSION

The demographics and clinical parameters were comparable with other studies. Two eyes with preoperative dehiscence on ASOCT had intact posterior capsule during surgery. The cause can be a dense opacity with increased optical density causing an obscured a clear capsule view on ASOCT, an artifact defect, giving a false impression of dehiscence. One eye who had nondehiscent PC on ASOCT was found to have PCR on the table, which can be due to an extremely thin PC or tightly adherent polar opacity to the capsule. According to our study, the diagnostic accuracy of ASOCT for detecting preoperative dehiscence was 94.4% (sensitivity)and of nondehiscence was 87.5%(specificity). 97.1% of eyes with dehiscence on ASOCT, had actual posterior capsular rent (positive predictive value). To conclude, ASOCT can be used as a reliable diagnostic modality.

摘要

引言

后极性白内障(PPC)术前存在后囊膜裂开增加了术中后囊膜破裂的几率。我们的研究旨在证明术前眼前节光学相干断层扫描(ASOCT)预测PPC术中后囊膜破裂(PCR)的有效性。

材料与方法

这是一项观察性研究,纳入年龄在25至75岁之间、患有PPC且接受超声乳化手术的患者。进行ASOCT以评估术前的后囊膜状态,分为“完整”或“裂开”,最终记录术中后囊膜状态。

统计分析

使用SPSS(版本27.0),P值≤0.05被认为具有统计学意义。

结果

44只眼的ASOCT检查显示,9只眼(20.5%)后囊膜裂开,35只眼(79.5%)后囊膜完整。在这9只裂开的眼中,7只眼(77.8%)术中发生了PCR,2只眼(22.2%)未发生。在这35只眼中,34只眼(97.1%)术中后囊膜实际完整,1只眼(2.9%)术中发生了PCR。ASOCT检测裂开的敏感性和特异性分别为94.4%和87.5%。阳性预测值和阴性预测值分别为97.1和77.8。该检测的诊断准确性为95.45%,卡方值为27.01(P<0.0001)。ASOCT分级检测术前裂开的诊断有效性得到证实。术中PCR与术前裂开之间的关联具有统计学意义(卡方检验 - P<0.0001)。我们的目标得以实现。

讨论与结论

人口统计学和临床参数与其他研究相当。ASOCT显示术前裂开的两只眼在手术中后囊膜完整。原因可能是密度增加的致密混浊物导致ASOCT上后囊膜清晰视野被遮挡,这是一种伪像缺陷,给人裂开的错误印象。一只ASOCT显示后囊膜未裂开的眼在手术中被发现发生了PCR,这可能是由于后囊膜极薄或极性混浊物与囊膜紧密粘连。根据我们的研究,ASOCT检测术前裂开的诊断准确性为94.4%(敏感性),检测未裂开的诊断准确性为87.5%(特异性)。ASOCT显示裂开的眼中97.1%实际发生了后囊膜破裂(阳性预测值)。总之,ASOCT可作为一种可靠的诊断方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92a6/10433076/b84609ec1c89/OJO-16-244-g001.jpg

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