Ungureanu Larisa, Chaudhuri K Ray, Diaconu Stefania, Falup-Pecurariu Cristian
Department of Neurology, County Clinic Hospital, Braşov, Romania.
Faculty of Medicine, Transilvania University, Braşov, Romania.
Front Neurol. 2023 Aug 1;14:1236366. doi: 10.3389/fneur.2023.1236366. eCollection 2023.
In Parkinson's disease (PD) patients, a wide range of ocular and visual disorders are present. Tear film instability, inflammation and dysfunction of the ocular surface, and the presence of symptoms of visual disturbance characterize dry eye, a multifactorial disease of the ocular surface. Based on a literature search, we discuss the frequency, pathogenesis, and influence on the quality of life of patients with dry eye in Parkinson's disease. Furthermore, we review the available means of diagnosis and management of dry eye. An improvement in awareness and recognition of dry eye is needed to provide suitable, personalized therapeutic options for PD patients, aiming to improve their quality of life, independence, and safety.
在帕金森病(PD)患者中,存在多种眼部和视觉障碍。泪膜不稳定、眼表炎症和功能障碍以及视觉干扰症状的存在是干眼的特征,干眼是一种眼表的多因素疾病。基于文献检索,我们讨论了帕金森病患者干眼的发生率、发病机制及其对患者生活质量的影响。此外,我们还综述了干眼的现有诊断和治疗方法。需要提高对干眼的认识和识别,以便为帕金森病患者提供合适的、个性化的治疗选择,旨在提高他们的生活质量、独立性和安全性。