SBU Sisli Hamidiye Etfal Training and Research Hospital, Pediatrics, MD, Istanbul, Turkey.
Division of Pediatric Gastroenterology, SBU Sisli Hamidiye Etfal Training and Research Hospital, Kazim Karabekir Pasa, Bahcekoy No: 62 Sariyer, Istanbul, Turkey.
Eur J Pediatr. 2023 Nov;182(11):4949-4955. doi: 10.1007/s00431-023-05165-z. Epub 2023 Aug 22.
Functional gastrointestinal disorders (FGID) are disorders of gut-brain interactions characterized by chronic recurrent gastrointestinal symptoms and are reported to be more common in obese individuals. The aim of the study was to evaluate FGID in obese children. A total of 405 children (6-18 years) were enrolled in this cross sectional study. The children were divided into two groups according to body mass index (BMI) as < 85th percentile and > 95th percentile. Diagnosis of FGID was based on ROME VI criteria. Demographic and clinical characteristics of the patients were evaluated. FGID and subgroups were determined. The mean age of the children was 12.73 ± 3.17 years; 52% (n = 211) of them was female and 47.9% (n = 194) was male. A total of 50.6% patients had BMI > 95th percentile, and 55.1% of those patients had FGID. The subgroups of FGID, functional abdominal pain disorders and functional defecation disorders were significantly more common in obese children than non-obese group (P < 0.01). Additionally, constipation-predominant irritable bowel syndrome (IBS), diarrhea-predominant IBS, functional diarrhea, and abdominal distention were significantly more common in obese children than non-obese children (P < 0.01).
FGID in obese children was found to be increased significantly. Assessment of functional gastrointestinal symptoms in obese children will prevent unnecessary examinations.
• Functional gastrointestinal disorders are reported to be more common in obese individuals.
• Functional abdominal pain disorders and functional defecation disorders were significantly more common in obese children than non-obese group. • Constipation-predominant irritable bowel syndrome (IBS), diarrhea-predominant IBS, functional diarrhea, and abdominal distention were significantly more common in obese children than non-obese children.
评估肥胖儿童功能性胃肠病（FGID）的患病情况。
采用横断面研究方法，纳入 405 例 6-18 岁肥胖儿童，根据体质量指数（BMI）分为<85 百分位和>95 百分位两组，采用罗马 VI 标准诊断 FGID，评估两组儿童的一般临床资料、FGID 患病情况及亚型。
肥胖儿童 FGID 的总患病率为 55.1%，显著高于非肥胖儿童（P<0.01）；FGID 各亚型中，功能性腹痛障碍和功能性排便障碍在肥胖儿童中更为常见（P<0.01）；功能性腹泻、便秘型肠易激综合征（IBS）、腹泻型 IBS 和腹胀在肥胖儿童中也更为常见（P<0.01）。
肥胖儿童 FGID 患病率显著升高，评估肥胖儿童的功能性胃肠症状有助于避免不必要的检查。
