移植后患者以回盲部肿块为表现的弥漫性大 B 细胞淋巴瘤。
Diffuse large B-cell lymphoma presenting as an ileocaecal mass in a post-transplant patient.
机构信息
School of Medicine, University of California San Francisco, San Francisco, California, USA
Department of Pathology, University of California San Francisco, San Francisco, California, USA.
出版信息
BMJ Case Rep. 2023 Aug 22;16(8):e256166. doi: 10.1136/bcr-2023-256166.
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. Extranodal involvement, including the gastrointestinal tract, occurs frequently. However, colorectal involvement is extremely rare. We present a case of a man in his 20s with prior renal transplantation on immunosuppression for 10 years who developed symptoms of gas and bloating associated with unintentional weight loss. Colonoscopy revealed a large fungating mass at the ileocaecal valve, and a biopsy of this lesion confirmed stage IV DLBCL. Endoscopy should be considered for early workup of vague gastrointestinal symptoms, even in younger patients, if they have been on long-standing immunosuppression.
弥漫性大 B 细胞淋巴瘤（DLBCL）是最常见的非霍奇金淋巴瘤类型。结外累及，包括胃肠道，经常发生。然而，结直肠受累极为罕见。我们报告了一例 20 多岁的男性，他在免疫抑制治疗 10 年后接受了肾移植，出现了气胀和体重意外减轻的症状。结肠镜检查显示回盲瓣处有一个大的蕈样肿块，该病变的活检证实为 IV 期 DLBCL。如果年轻患者长期接受免疫抑制治疗，即使出现不明确的胃肠道症状，也应考虑进行内镜检查以进行早期检查。
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