Department of Urology, SUNY Upstate Medical University, Syracuse, NY, 13210, USA.
Upstate Cancer Center, SUNY Upstate Medical University, Syracuse, NY, 13210, USA.
Nat Commun. 2023 Aug 22;14(1):5084. doi: 10.1038/s41467-023-40713-z.
Molecular chaperones establish essential protein-protein interaction networks. Modified versions of these assemblies are generally enriched in certain maladies. A study published in used epichaperomics to identify unique changes occurring in chaperone-formed protein networks during mitosis in cancer cells.
分子伴侣建立了基本的蛋白质-蛋白质相互作用网络。这些组装体的修饰版本通常在某些疾病中富集。发表在[期刊名称]上的一项研究使用了表观组学来鉴定癌细胞有丝分裂过程中伴侣形成的蛋白质网络中发生的独特变化。
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