Jenkins W T, Patrick J S
J Inorg Biochem. 1986 Jul;27(3):163-72. doi: 10.1016/0162-0134(86)80057-5.
Calcium and magnesium catalyze the dephosphorylation of a molybdate complex of adenosine triphosphate but not the corresponding molybdate complex of adenosine disphosphate. We conclude that catalysis of breaking the bond between the beta and gamma phosphates involves metal chelation of the alpha and beta phosphates. ATP hydrolysis with calcium was stimulated by phosphate, apparently because of formation of a calcium-phosphomolybdate complex. The reaction with magnesium, which does not form a comparable complex, was not affected by phosphate. Strontium, cadmium, and barium behaved like calcium. The reactions with transition metal cations showed autoinhibition.
钙和镁催化三磷酸腺苷钼酸盐复合物的去磷酸化反应，但不催化二磷酸腺苷相应钼酸盐复合物的去磷酸化反应。我们得出结论，催化β和γ磷酸之间的键断裂涉及α和β磷酸的金属螯合作用。钙存在时，磷酸盐可刺激ATP水解，这显然是由于形成了钙 - 磷钼酸盐复合物。镁不存在类似的复合物形成，其反应不受磷酸盐影响。锶、镉和钡的行为与钙相似。过渡金属阳离子的反应表现出自抑制作用。
