Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada.
J Evol Biol. 2023 Sep;36(9):1328-1341. doi: 10.1111/jeb.14207. Epub 2023 Aug 23.
As a corollary to the Red Queen hypothesis, host-parasite coevolution has been hypothesized to maintain genetic variation in both species. Recent theoretical work, however, suggests that reciprocal natural selection alone is insufficient to maintain variation at individual loci. As highlighted by our brief review of the theoretical literature, models of host-parasite coevolution often vary along multiple axes (e.g. inclusion of ecological feedbacks or abiotic selection mosaics), complicating a comprehensive understanding of the effects of interacting evolutionary processes on diversity. Here we develop a series of comparable models to explore the effect of interactions between spatial structures and antagonistic coevolution on genetic diversity. Using a matching alleles model in finite populations connected by migration, we find that, in contrast to panmictic populations, coevolution in a spatially structured environment can maintain genetic variation relative to neutral expectations with migration alone. These results demonstrate that geographic structure is essential for understanding the effect of coevolution on biological diversity.
作为红皇后假说的推论，宿主-寄生虫协同进化被假设为维持两种物种的遗传变异。然而，最近的理论工作表明，仅相互的自然选择不足以维持个体基因座的变异。正如我们对理论文献的简要回顾所强调的那样，宿主-寄生虫协同进化的模型通常沿着多个轴变化（例如，包括生态反馈或非生物选择镶嵌体），这使得对相互作用的进化过程对多样性的影响的全面理解变得复杂。在这里，我们开发了一系列可比的模型来探索空间结构和拮抗协同进化之间的相互作用对遗传多样性的影响。我们使用有限种群中通过迁移连接的等位基因匹配模型发现，与混合种群相比，在空间结构环境中的协同进化可以仅通过迁移来维持相对于中性预期的遗传变异。这些结果表明，地理结构对于理解协同进化对生物多样性的影响至关重要。
