Casanova C, Molotchnikoff S
J Physiol (Paris). 1986;81(1):7-13.
These investigations are aimed at studying the influence of the electrical stimulation of the VIth nucleus (abducens nucleus) on responses of lateral geniculate cells in rabbits. The animals were prepared in the usual fashion for single cell recordings at the lateral geniculate nucleus (LGN). Results show that: Electrical stimulation of the VIth nucleus always produced excitatory discharges whose latency varied from 30 to 400 ms. Interestingly, an electrical pulse applied to the abducens nucleus was capable of enhancing the light-evoked responses without altering the spontaneous rate of firing. It thus seems that the ascending influence of the VIth nucleus manifests itself when it coincides with light responses. Most cells which were sensitive to electrical activation of the abducens nucleus had their receptive field located peripherally (greater than 50 degrees). Histological reconstructions of recording electrode tracts suggest that cells which responded to electrical stimulation were located in a narrow band lying dorsally relative to the LGN. This area can be paralleled with the perigeniculate area observed in other mammals, although not identified in rabbits. It is suggested that these extraretinal impulses which reach the LGN and emerge from an area surrounding the VIth nucleus are associated with corollary discharges.
这些研究旨在探讨对兔外展神经核（第六神经核）进行电刺激对外侧膝状体细胞反应的影响。按照常规方法对动物进行准备，以便在外侧膝状体核（LGN）进行单细胞记录。结果表明：对第六神经核的电刺激总是产生兴奋性放电，其潜伏期在30至400毫秒之间变化。有趣的是，施加于外展神经核的电脉冲能够增强光诱发反应，而不改变自发放电率。因此，似乎第六神经核的上行影响在与光反应同时出现时表现出来。大多数对外展神经核电激活敏感的细胞，其感受野位于周边（大于50度）。记录电极轨迹的组织学重建表明，对电刺激有反应的细胞位于相对于LGN背侧的一条窄带中。该区域可与在其他哺乳动物中观察到的膝状体周围区域相类比，尽管在兔中未被识别。有人提出，这些到达LGN并来自第六神经核周围区域的视网膜外冲动与伴随放电有关。
