Department of Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Int J Immunopathol Pharmacol. 2023 Jan-Dec;37:3946320231190898. doi: 10.1177/03946320231190898.
Hepatocellular carcinoma is a prevalent malignant tumor affecting the liver, and surgical resection and liver transplantation are the primary treatment options for early-stage HCC patients. However, the presence of benign hepatic tumors with similar imaging characteristics to HCC poses challenges in diagnosing and treating the disease, often resulting in misdiagnosis and inappropriate treatment. This case report presents a 52-year-old female patient who exhibited space-occupying liver lesions on abdominal CT and MRI scans. Based on pathological sections from other hospitals, liver malignancy was highly suspected, and hepatocellular tumor was diagnosed preoperatively. But the tumor markers of the patient were all within the normal range. After evaluating the overall condition of the patient, we finally chose the diagnosis and treatment of dissection and partial hepatectomy. Surprisingly, the final diagnosis of postoperative pathology was sclerosing hemangioma. The patient recovered well and was discharged 2 weeks later. Hepatic sclerosing hemangioma is an extremely rare disease that can be easily mistaken for malignant liver tumors due to absence of typical imaging presentations. The diagnosis also needs to be differentiated from other benign tumors, such as liver adenoma and liver abscess, according to the medical history, symptoms, and auxiliary examinations. Therefore, special attention should be given to the diagnosis and treatment of sclerosing hemangioma.
肝细胞癌是一种常见的肝脏恶性肿瘤,手术切除和肝移植是早期 HCC 患者的主要治疗选择。然而,具有与 HCC 相似影像学特征的良性肝肿瘤的存在给疾病的诊断和治疗带来了挑战,往往导致误诊和不适当的治疗。本病例报告介绍了一位 52 岁女性患者,其腹部 CT 和 MRI 扫描显示有空占位性肝病变。根据其他医院的病理切片,高度怀疑为肝恶性肿瘤,术前诊断为肝细胞肿瘤。但患者的肿瘤标志物均在正常范围内。在评估了患者的整体情况后,我们最终选择了解剖和部分肝切除术的诊断和治疗。令人惊讶的是,术后病理最终诊断为硬化性血管瘤。患者恢复良好,两周后出院。肝硬化性血管瘤是一种非常罕见的疾病,由于缺乏典型的影像学表现,很容易误诊为恶性肝肿瘤。根据病史、症状和辅助检查,还需要与其他良性肿瘤如肝腺瘤和肝脓肿相鉴别。因此,对硬化性血管瘤的诊断和治疗应给予特别关注。