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本文引用的文献

1
World Gastroenterology Organisation global guidelines: Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.世界胃肠病学组织全球指南:非酒精性脂肪性肝病和非酒精性脂肪性肝炎
J Clin Gastroenterol. 2014 Jul;48(6):467-73. doi: 10.1097/MCG.0000000000000116.
2
Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil.非酒精性脂肪性肝炎和非肝硬化性肝细胞癌:肥沃的土壤。
Semin Liver Dis. 2012 Feb;32(1):30-8. doi: 10.1055/s-0032-1306424. Epub 2012 Mar 13.
3
Outcomes of curative treatment for hepatocellular cancer in nonalcoholic steatohepatitis versus hepatitis C and alcoholic liver disease.非酒精性脂肪性肝炎与丙型肝炎和酒精性肝病患者行根治性治疗的肝细胞癌结局比较。
Hepatology. 2012 Jun;55(6):1809-19. doi: 10.1002/hep.25536. Epub 2012 Apr 23.
4
Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma.非酒精性脂肪性肝炎患者发生肝细胞癌的特征。
Clin Gastroenterol Hepatol. 2011 May;9(5):428-33; quiz e50. doi: 10.1016/j.cgh.2011.01.023. Epub 2011 Feb 12.
5
Epidemiology of non-alcoholic fatty liver disease.非酒精性脂肪性肝病的流行病学。
Dig Dis. 2010;28(1):155-61. doi: 10.1159/000282080. Epub 2010 May 7.
6
Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection.非酒精性脂肪性肝病与肝细胞癌:沉甸甸的关联。
Hepatology. 2010 May;51(5):1820-32. doi: 10.1002/hep.23594.
7
Hepatocellular carcinoma and non-alcoholic fatty liver disease: from a clinical to a molecular association.肝细胞癌和非酒精性脂肪性肝病:从临床关联到分子关联。
Curr Pharm Des. 2010;16(6):741-52. doi: 10.2174/138161210790883787.
8
Prospective study of hepatocellular carcinoma in nonalcoholic steatohepatitis in comparison with hepatocellular carcinoma caused by chronic hepatitis C.非酒精性脂肪性肝炎相关肝细胞癌与慢性丙型肝炎相关肝细胞癌的前瞻性研究。
J Gastroenterol. 2010 Sep;45(9):960-7. doi: 10.1007/s00535-010-0237-1. Epub 2010 Apr 8.
9
Nonalcoholic steatohepatitis-associated hepatocellular carcinoma: our case series and literature review.非酒精性脂肪性肝炎相关肝细胞癌:我们的病例系列及文献复习。
World J Gastroenterol. 2010 Mar 28;16(12):1436-41. doi: 10.3748/wjg.v16.i12.1436.
10
Pathogenesis of non-alcoholic fatty liver disease.非酒精性脂肪性肝病的发病机制。
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非酒精性脂肪性肝病中酷似良性血管瘤的肝细胞癌:两例报告及文献复习

Hepatocellular carcinoma in nonalcoholic fatty liver disease mimicking benign hemangioma: two case reports and literature review.

作者信息

Tan Haidong, Xu Li, Liu Xiaolei, Si Shuang, Sun Yongliang, Liu Liguo, Zhou Wenying, Yang Zhiying

机构信息

Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.

出版信息

Int J Clin Exp Pathol. 2015 Nov 1;8(11):15350-5. eCollection 2015.

PMID:26823893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4713679/
Abstract

OBJECTIVE

To study the clinical features of nonalcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma (HCC).

METHODS

The clinical manifestations, imaging features, pathological subtypes and treatment outcome of two cases with NAFLD-associated HCC were analyzed.

RESULTS

In these two cases, both were young, obese male patients, with contrast enhanced CT scan of hemangioma-like features. They had undergone surgical resection and both were reported as well-differentiated HCC pathologically. They were followed-up respectively up to 46 and 36 months post-operatively with no evidence of recurrence or metastasis.

CONCLUSIONS

NAFLD-associated HCC has different radiological presentations from typical HCC. Incidental finding of any liver occupying lesions in NAFLD patients should raise immediate clinical attention.

摘要

目的

研究非酒精性脂肪性肝病(NAFLD)相关肝细胞癌(HCC)的临床特征。

方法

分析2例NAFLD相关HCC患者的临床表现、影像学特征、病理亚型及治疗结果。

结果

这2例患者均为年轻肥胖男性,增强CT扫描表现为血管瘤样特征。他们均接受了手术切除,病理报告均为高分化HCC。术后分别随访46个月和36个月,均无复发或转移迹象。

结论

NAFLD相关HCC具有与典型HCC不同的影像学表现。NAFLD患者偶然发现肝脏占位性病变应立即引起临床关注。