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“你为什么不想要我的粪便?”志愿粪便捐赠者因不合格而无法捐赠肠道微生物组的经历。

"Why don't you want my poop?" Willing stool donor's experiences of being ineligible to donate intestinal microbiota.

机构信息

School of Psychology, The University of Queensland, St Lucia, Queensland, Australia.

Strategy and Growth, Australian Red Cross Lifeblood, Melbourne, Victoria, Australia.

出版信息

Transfusion. 2023 Oct;63(10):1916-1925. doi: 10.1111/trf.17516. Epub 2023 Aug 24.

DOI:10.1111/trf.17516
PMID:37615344
Abstract

BACKGROUND

Blood collection agencies (BCAs) hosting stool (fecal or poo) donor programs report high rates of donor deferral. However, the impact of deferral on willing donors, in terms of personal well-being and future engagement with BCAs, remains unexplored. Accordingly, we surveyed those attempting to donate intestinal microbiota about their experience of being ineligible.

STUDY DESIGN AND METHODS

A total of 196 potential stool donors from Australia's BCA (>90% blood/blood product donors) completed the first stage of eligibility screening and then an online survey once notified of their ineligibility. Respondents reported motives for donating, perceptions of screening and improvements needed, experience of being told they are ineligible, and their feelings about this.

RESULTS

Over 80% of participants were ineligible to donate. Of those ineligible, 58% did not know why they were ineligible resulting in potentially future eligible donors being permanently lost. Motives (>5%) included helping others, being a human substance donor, understanding benefits, curiosity/novelty, and helping science/research. Participants identified they needed clear and timely information during screening and a specific reason for their ineligibility. Participants commonly experienced disappointment, confusion, and calm in response to being ineligible.

DISCUSSION

BCAs need strategies to mitigate the disappointment of ineligible donors, maintain satisfaction with BCAs, and preserve donor identity since many ineligible donors give multiple human substances. BCAs should provide more information about eligibility criteria during early screening stages to reduce disappointment and give personalized information about ineligibility to resolve the confusion. Offering alternative opportunities to give may reduce disappointment and increase ineligible donor engagement.

摘要

背景

主办粪便(粪便或粪便)捐赠计划的血液采集机构(BCA)报告称,捐赠者的拒绝率很高。然而,在个人幸福感和未来与 BCA 的参与度方面,拒绝对愿意捐赠的人有何影响仍未得到探索。因此,我们调查了那些试图捐赠肠道微生物群的人,了解他们不符合条件的经历。

研究设计和方法

来自澳大利亚 BCA 的 196 名潜在粪便捐赠者(超过 90%的血液/血液制品捐赠者)完成了资格筛选的第一阶段,然后在得知自己不合格后完成了在线调查。受访者报告了捐赠动机、对筛选的看法和需要改进的地方、被告知不合格的经历以及对此的感受。

结果

超过 80%的参与者不符合捐赠条件。在不合格者中,58%的人不知道自己为什么不合格,这可能导致潜在的合格捐赠者永久流失。动机(超过 5%)包括帮助他人、成为人体物质捐赠者、了解益处、好奇心/新奇感以及帮助科学/研究。参与者认为他们在筛选过程中需要清晰和及时的信息以及不合格的具体原因。参与者通常对不合格感到失望、困惑和冷静。

讨论

BCA 需要采取策略来减轻不合格捐赠者的失望情绪,保持对 BCA 的满意度,并保护捐赠者的身份,因为许多不合格的捐赠者会提供多种人体物质。BCA 应在早期筛选阶段提供更多关于资格标准的信息,以减少失望,并提供有关不合格的个性化信息,以解决困惑。提供替代捐赠机会可能会减少失望并增加不合格捐赠者的参与度。

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