Furukawa S, Okada T
Jpn J Antibiot. 1986 Apr;39(4):1128-37.
We used cefixime (CFIX), a newly developed oral cephalosporin antibiotic, to treat 21 children with various infections. The results are summarized as follows. The serum half-lives of CFIX after an administration of 6 mg/kg to each of 2 children were 2.56 and 2.79 hours. The serum concentrations were high enough to ensure the therapeutic response. The clinical response was "excellent" in 16 children and "good" in 5, with a 100% efficacy rate. No side effects were recorded. The only abnormal finding was slight eosinophilia in 1 child.
我们使用了新开发的口服头孢菌素抗生素头孢克肟（CFIX）来治疗21名患有各种感染的儿童。结果总结如下。给2名儿童每人服用6mg/kg的CFIX后，其血清半衰期分别为2.56小时和2.79小时。血清浓度足够高，足以确保治疗反应。16名儿童的临床反应为“优秀”，5名儿童为“良好”，有效率达100%。未记录到副作用。唯一的异常发现是1名儿童出现轻微嗜酸性粒细胞增多。
