Satariano Matthew, Losinski Emily, Lane Jason, Wegryn John
Northeast Ohio Medical University, 4209 St. Rt. 44, PO Box 95, Rootstown, OH, 44272, United States.
Department of Urology, Cleveland Clinic Akron General, 1 Akron General Ave, Akron, OH, 44307, United States.
Urol Case Rep. 2023 Aug 16;50:102532. doi: 10.1016/j.eucr.2023.102532. eCollection 2023 Sep.
Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such as positivity for steroidogenic factor 1 (SF1), calretinin, and inhibin A. We present a case of a 39-year-old male with an adult GCT of the testicle who underwent successful unilateral orchiectomy. This case adds to the body of literature and furthers our understanding of tumor histopathology, tumor behavior, clinical surveillance, and treatment strategies for this testicular neoplasm.
睾丸颗粒细胞瘤(GCTs)是性索间质肿瘤的一种罕见亚型,通常表现为无痛性睾丸肿大。成人睾丸GCT的组织学特征常类似于正常颗粒细胞组织形态,具有相似的免疫组化染色模式,如类固醇生成因子1(SF1)、钙视网膜蛋白和抑制素A呈阳性。我们报告一例39岁成年男性睾丸GCT患者,该患者成功接受了单侧睾丸切除术。此病例丰富了文献资料,并加深了我们对这种睾丸肿瘤的组织病理学、肿瘤行为、临床监测及治疗策略的理解。