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睾丸成人型颗粒细胞瘤:病例报告

Adult-type granulosa cell tumor of the testicle: case report.

作者信息

Halalsheh Omar, Al-Mohtaseb Alia, Al-Karasneh Anas Ibrahim, Al-Janabi Mustafa Mokhalad, Hallak Amer Hussein

机构信息

Department of Surgery and Urology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Department of Pathology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

出版信息

Res Rep Urol. 2019 Jun 24;11:189-193. doi: 10.2147/RRU.S208556. eCollection 2019.

Abstract

Granulosa cell tumor (GCT) is a sex-cord neoplasm of the gonads classified into either juvenile (jGrCT) or adult type (aGrCT). It is commonly arising in ovaries but is much rarer in men, with only around 50 male cases previously reported in the literature. We report on a 54-year-old male patient with a right testicular GCT measuring 10.0×8.0×6.0 cm. The tumor was treated successfully with radical orchiectomy followed by computed tomography to assess lymph node involvement, and no further treatment was done. Pathological reports showed diffuse positivity for immunohistochemical stains, inhibin, vimentin, calretinin, and CD99. The clinical and histopathological features, treatment, and prognosis of aGrCT arising in the testicle of an adult male are also reviewed in this manuscript.

摘要

颗粒细胞瘤(GCT)是一种性腺的性索肿瘤,分为青少年型(jGrCT)或成人型(aGrCT)。它通常发生于卵巢,但在男性中较为罕见,文献中此前仅报道过约50例男性病例。我们报告一例54岁男性患者,其右侧睾丸颗粒细胞瘤大小为10.0×8.0×6.0 cm。该肿瘤通过根治性睾丸切除术成功治疗,随后进行计算机断层扫描以评估淋巴结受累情况,未进行进一步治疗。病理报告显示免疫组化染色、抑制素、波形蛋白、钙视网膜蛋白和CD99呈弥漫阳性。本文还回顾了成年男性睾丸中发生的成人型颗粒细胞瘤的临床和组织病理学特征、治疗及预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c75/6598752/ad77a43cd35a/RRU-11-189-g0001.jpg

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