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柠檬草(香茅)的药理学。II. 对雄性和雌性大鼠以及“子宫内”暴露的后代进行为期两个月的每日给药的影响。

Pharmacology of lemongrass (Cymbopogon citratus Stapf). II. Effects of daily two month administration in male and female rats and in offspring exposed "in utero".

作者信息

Souza Formigoni M L, Lodder H M, Gianotti Filho O, Ferreira T M, Carlini E A

出版信息

J Ethnopharmacol. 1986 Jul;17(1):65-74. doi: 10.1016/0378-8741(86)90073-5.

Abstract

An infusion (abafado) prepared from leaves of lemongrass (Cymbopogon citratus Stapf) administered orally to adult rats for 2 months, in doses up to 20 times larger than the estimated corresponding human dosage, did not induce any effect which could be taken as evidence of toxicity. An absence of effects was also noted in male and female rats and in their offspring when the abafado was administered prior to mating or during pregnancy. These data strongly suggest that lemongrass, as used in Brazilian folk medicine, has no toxic properties.

摘要

将从柠檬草(Cymbopogon citratus Stapf)叶子制备的浸剂口服给予成年大鼠2个月,剂量高达估计相应人类剂量的20倍,未产生任何可被视为毒性证据的影响。当在交配前或怀孕期间给予浸剂时,在雄性和雌性大鼠及其后代中也未观察到任何影响。这些数据有力地表明,巴西民间医学中使用的柠檬草没有毒性。

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