Antiñolo Bermúdez Laura, Martínez Sánchez Elena María, Leyva Díaz Juan Carlos, Muñio Martínez María Del Mar, Poyatos Capilla Jose Manuel, Martín Pascual Jaime
Department of Civil Engineering, Institute of Water Research, University of Granada, 18071 Granada, Spain.
Department of Chemical Engineering, University of Granada, 18071 Granada, Spain.
Membranes (Basel). 2023 Jul 27;13(8):697. doi: 10.3390/membranes13080697.
The occurrence of emerging organic contaminants, such as pharmaceuticals, is a growing global concern. In this research, for a membrane bioreactor (MBR) laboratory plant operating at a hydraulic retention time (HRT) of 24 h, fed with real urban wastewater, the heterotrophic biomass behaviour was analysed for two concentrations of erythromycin, ibuprofen, and diclofenac. The concentrations studied for the first phase were erythromycin 0.576 mg L, ibuprofen 0.056 mg L, and diclofenac 0.948 mg L. For Phase 2, the concentrations were increased to erythromycin 1.440 mg L, ibuprofen 0.140 mg L, and diclofenac 2.370 mg L. Heterotrophic biomass was affected and inhibited by the presence of pharmaceutical compounds in both phases. The system response to low concentrations of pharmaceutical compounds occurred in the initial phase of plant doping. Under these operating conditions, there was a gradual decrease in the concentration of mixed liquor suspended solids and the removal of chemical oxygen demand of the system, as it was not able to absorb the effect produced by the pharmaceutical compounds added in both phases.
新兴有机污染物（如药物）的出现是一个日益引起全球关注的问题。在本研究中，对于一个水力停留时间（HRT）为24小时、以实际城市污水为进水的膜生物反应器（MBR）实验室装置，分析了两种浓度的红霉素、布洛芬和双氯芬酸存在下的异养生物质行为。第一阶段研究的浓度为红霉素0.576 mg/L、布洛芬0.056 mg/L和双氯芬酸0.948 mg/L。对于第二阶段，浓度增加到红霉素1.440 mg/L、布洛芬0.140 mg/L和双氯芬酸2.370 mg/L。在两个阶段中，药物化合物的存在均对异养生物质产生了影响并起到了抑制作用。系统对低浓度药物化合物的响应发生在装置投加药物的初始阶段。在这些运行条件下，混合液悬浮固体浓度逐渐降低，系统的化学需氧量去除率也下降，因为它无法吸收两个阶段添加的药物化合物所产生的影响。
