Department of Neurological Surgery, Weill Cornell Medicine/New York Presbyterian Hospital, New York, New York, USA.
Department of Neurological Surgery, Weill Cornell Medicine/New York Presbyterian Hospital, New York, New York, USA.
World Neurosurg. 2023 Nov;179:100-101. doi: 10.1016/j.wneu.2023.08.079. Epub 2023 Aug 23.
Trigeminal neuralgia, or tic douloureux, clinically presents as a unilateral paroxysmal, stabbing, intense pain of the face, lasting for seconds but occurring frequently. Alternative causes including multiple sclerosis or mass of the brainstem or cranial nerves must be ruled out. Medical treatment, most commonly with carbamazepine, remains an effective first-line treatment. Ultimately, if medical management becomes refractory or symptoms progressive, then procedural and surgical options including microvascular decompression, stereotactic radiosurgery, radiofrequency thermocoagulation, and others should be considered. Most notably, microvascular decompression, as in this case, can be considered with an 85%-95% initial success rate.
三叉神经痛,又称痛性抽搐,临床上表现为单侧阵发性、刺痛样剧烈疼痛,持续数秒,但频繁发作。需要排除多发性硬化症或脑干或颅神经肿块等其他病因。最常见的治疗方法是卡马西平,仍然是有效的一线治疗方法。最终,如果药物治疗无效或症状进展,那么可以考虑采用程序性和手术性治疗方法,包括微血管减压术、立体定向放射外科、射频热凝术等。值得注意的是,如本例所示,微血管减压术的初始成功率可达 85%至 95%。