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本文引用的文献

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Feasibility of implementing a supervised telehealth exercise intervention in frail survivors of hematopoietic cell transplantation: a pilot randomized trial.在造血细胞移植后虚弱幸存者中实施监督远程医疗运动干预的可行性:一项试点随机试验。
BMC Cancer. 2023 May 1;23(1):390. doi: 10.1186/s12885-023-10884-5.
2
Personalizing the Setting of Palliative Care Delivery for Patients with Advanced Cancer: "Care Anywhere, Anytime".为晚期癌症患者个性化姑息治疗的实施环境:“随时随地的关怀”。
Curr Treat Options Oncol. 2023 Jan;24(1):1-11. doi: 10.1007/s11864-022-01044-1. Epub 2022 Dec 28.
3
Pilot Trial of Homebound Hematopoietic Cell Transplantation.居家血液干细胞移植的初步试验。
Transplant Cell Ther. 2022 Dec;28(12):832.e1-832.e7. doi: 10.1016/j.jtct.2022.09.014. Epub 2022 Sep 29.
4
An evidence-based practice guideline of the National Society of Genetic Counselors for telehealth genetic counseling.《全国遗传咨询师协会基于证据的远程医疗遗传咨询实践指南》。
J Genet Couns. 2023 Feb;32(1):4-17. doi: 10.1002/jgc4.1627. Epub 2022 Aug 30.
5
Telehealth in hematopoietic cell transplantation: perspective from patients at a public hospital in Brazil.造血细胞移植中的远程医疗:来自巴西一家公立医院患者的观点。
Bone Marrow Transplant. 2022 Nov;57(11):1735-1736. doi: 10.1038/s41409-022-01782-8. Epub 2022 Aug 31.
6
The SMILe integrated care model in allogeneic SteM cell TransplantatIon faciLitated by eHealth: a protocol for a hybrid effectiveness-implementation randomised controlled trial.SMILe 整合照护模式在异体干细胞移植中的应用:一项基于电子健康的混合有效性-实施随机对照试验方案。
BMC Health Serv Res. 2022 Aug 20;22(1):1067. doi: 10.1186/s12913-022-08293-8.
7
Feasibility of outpatient administration of axicabtagene ciloleucel and brexucabtagene autoleucel using telemedicine tools: The Vanderbilt experience.使用远程医疗工具进行阿基仑赛和贝林妥欧单抗门诊给药的可行性:范德比尔特经验
Br J Haematol. 2022 Sep;198(6):1073-1075. doi: 10.1111/bjh.18339. Epub 2022 Jun 28.
8
Telemedicine and Its Past, Present, and Future Roles in Providing Palliative Care to Advanced Cancer Patients.远程医疗在为晚期癌症患者提供姑息治疗方面的过去、现在及未来作用
Cancers (Basel). 2022 Apr 8;14(8):1884. doi: 10.3390/cancers14081884.
9
Safety and feasibility of outpatient chimeric antigen receptor (CAR) T-cell therapy: experience from a tertiary care center.门诊嵌合抗原受体(CAR)T细胞疗法的安全性与可行性:来自三级医疗中心的经验
Bone Marrow Transplant. 2022 Jun;57(6):1025-1027. doi: 10.1038/s41409-022-01664-z. Epub 2022 Apr 11.
10
Home-Based Hematopoietic Cell Transplantation in the United States.美国的家庭为基础的造血细胞移植。
Transplant Cell Ther. 2022 Apr;28(4):207.e1-207.e8. doi: 10.1016/j.jtct.2022.01.015. Epub 2022 Jan 20.

造血细胞移植和嵌合抗原受体T细胞疗法中的远程医疗

Telemedicine in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor-T Cell Therapy.

作者信息

Gandhi Arpita P, Lee Catherine J

机构信息

Center for Hematologic Malignancies, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.

Fred Hutch Cancer Research Center, Clinical Research Division, Seattle, WA 98109, USA.

出版信息

Cancers (Basel). 2023 Aug 15;15(16):4108. doi: 10.3390/cancers15164108.

DOI:10.3390/cancers15164108
PMID:37627136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10452361/
Abstract

Telemedicine has played an important role in delivering healthcare for primary care, chronic disease patients, and those with solid organ malignancies. However, its application in subspecialties such as hematologic malignancies, hematopoietic cell transplantation (HCT), or chimeric antigen receptor-T cell (CAR-T) therapy is not widespread since physical examination is a vital component in delivering care. During the COVID-19 pandemic, we widely used telemedicine, since protecting our immunocompromised patients became our top priority. The employment of HCT and CAR-T therapies continues to grow for high-risk hematologic malignancies, particularly in older and frail patients who must visit specialty centers for treatment access. Generally, HCT and CAR-T therapy care is highly complex, necessitating commitment from patients, caregivers, and a multidisciplinary team at specialty academic centers. All healthcare systems adapted to the crisis and implemented rapid changes during the COVID-19 public health emergency (PHE). Telemedicine, a vital modality for delivering healthcare in underserved areas, experienced rapid expansion, regardless of the geographic region, during the COVID-19 PHE. The data emerging from practices implemented during the PHE are propelling the field of telemedicine forward, particularly for specialties with complex medical treatments such as HCT and CAR-T therapy. In this review, we examine the current data on telemedicine in HCT and cellular therapy care models for the acute and long-term care of our patients.

摘要

远程医疗在为初级保健、慢性病患者以及实体器官恶性肿瘤患者提供医疗服务方面发挥了重要作用。然而,由于体格检查是提供医疗服务的重要组成部分,其在血液系统恶性肿瘤、造血细胞移植(HCT)或嵌合抗原受体T细胞(CAR-T)治疗等亚专业领域的应用并不广泛。在新冠疫情期间,我们广泛使用了远程医疗,因为保护免疫功能低下的患者成为了我们的首要任务。对于高危血液系统恶性肿瘤,尤其是那些必须前往专科中心接受治疗的老年体弱患者,HCT和CAR-T疗法的应用持续增加。一般来说,HCT和CAR-T治疗护理非常复杂,需要患者、护理人员以及专科学术中心的多学科团队共同努力。在新冠公共卫生紧急事件(PHE)期间,所有医疗系统都适应了危机并迅速做出了改变。远程医疗作为在服务不足地区提供医疗服务的重要方式,在新冠PHE期间,无论地理区域如何,都经历了快速扩张。PHE期间实施的实践所产生的数据正在推动远程医疗领域向前发展,特别是对于HCT和CAR-T治疗等具有复杂医疗手段的专科领域。在本综述中,我们研究了关于远程医疗在HCT以及我们患者的急性和长期护理细胞治疗护理模式方面的当前数据。