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癌胚抗原和组织多肽抗原测定在乳腺癌转移诊断中的意义

Significance of carcinoembryonic and tissue polypeptide antigen determination in the diagnosis of metastases in breast cancer.

作者信息

Kausitz J, Hupka S, Makaiová I, Michalíková B, Urbanová M, Bohunický L, Belovicová C

出版信息

Neoplasma. 1986;33(4):471-6.

PMID:3762808
Abstract

A radioimmunological assay of CEA and TPA levels in breast cancer patients revealed a 93.7% concordance of negative and 93.4% of positive values with the clinical activity of the disease. In 26 out of a group of 38 patients (68.4%) with progressive breast carcinoma, an enhanced CEA and TPA level was the first indicator of the presence of metastases. In view of the results obtained, the authors consider this procedure to be a suitable method for monitoring and early detection of metastases in patients with breast cancer.

摘要

一项针对乳腺癌患者癌胚抗原(CEA)和组织多肽抗原(TPA)水平的放射免疫分析显示,阴性值与疾病临床活动的一致性为93.7%,阳性值为93.4%。在一组38例进行性乳腺癌患者中,有26例(68.4%)CEA和TPA水平升高是转移存在的首要指标。鉴于所获得的结果,作者认为该方法是监测和早期发现乳腺癌患者转移的合适方法。

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