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波兰一家三级医院肿瘤科住院儿科患者的感染情况。

Infections among Pediatric Patients Hospitalized at an Oncology Department of a Tertiary Hospital in Poland.

机构信息

Department of Management and Logistics in Healthcare, Medical University of Lodz, 90-419 Lodz, Poland.

Department of Nutrition and Epidemiology, Medical University of Lodz, 90-419 Lodz, Poland.

出版信息

Medicina (Kaunas). 2023 Jul 25;59(8):1363. doi: 10.3390/medicina59081363.

DOI:10.3390/medicina59081363
PMID:37629653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10456884/
Abstract

: Gastrointestinal tract infections caused by bacteria are diagnosed in pediatric patients with increasing frequency. Children treated at pediatric units are a group of patients at high risk of this infection; therefore, appropriate differential diagnostics and an individual approach to every case are of particular importance. The goal of the study was to assess the clinical parameters of patients with a confirmed CD infection and colonization. : Every positive case was subjected to a retrospective analysis based on medical history and an infection notification note. : Positive results were obtained for 30 patients, among whom the results of 18 patients were considered to justify the diagnosis of an infection. In the remaining patients, treatment was not initiated in only three cases. Cases were detected where treatment was initiated despite the lack of sufficient clinical evidence. : This study demonstrates that there are many factors that result in a high risk of the occurrence of CDI in oncology patients, such as antibiotic therapy, multiple hospitalizations, and myelosuppression.

摘要

: 由细菌引起的胃肠道感染在儿科患者中的诊断频率越来越高。在儿科病房接受治疗的儿童是该感染高危人群;因此,对每个病例进行适当的鉴别诊断和个体化治疗非常重要。本研究的目的是评估确诊 CD 感染和定植患者的临床参数。 : 对每例阳性病例均基于病史和感染通知记录进行回顾性分析。 : 共获得 30 例阳性结果,其中 18 例患者的结果足以诊断为感染。在其余患者中,仅在 3 例中未启动治疗。尽管缺乏充分的临床证据,但仍启动了治疗。 : 本研究表明,导致肿瘤患者 CDI 发生风险增加的因素很多,如抗生素治疗、多次住院和骨髓抑制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/f1076b72c29d/medicina-59-01363-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/96d9af8fc0f2/medicina-59-01363-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/e96cc43cea57/medicina-59-01363-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/f1076b72c29d/medicina-59-01363-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/96d9af8fc0f2/medicina-59-01363-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/e96cc43cea57/medicina-59-01363-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aec/10456884/f1076b72c29d/medicina-59-01363-g003.jpg

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本文引用的文献

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The Hospital Environment as a Potential Source for Transmission Based on Spore Detection Surveys Conducted at Paediatric Oncology and Gastroenterology Units.基于儿科肿瘤学和胃肠病学单位进行的孢子检测调查,医院环境作为潜在传播源。
Int J Environ Res Public Health. 2023 Jan 15;20(2):1590. doi: 10.3390/ijerph20021590.
2
Detection and Analysis of Spores in a Hospital Environment.医院环境中孢子的检测与分析。
Int J Environ Res Public Health. 2022 Nov 25;19(23):15670. doi: 10.3390/ijerph192315670.
3
Clostridium difficile Colonization Before and After Hospitalization in Children.
儿童住院前后艰难梭菌定植情况
Turk Arch Pediatr. 2021 Nov;56(6):585-590. doi: 10.5152/TurkArchPediatr.2021.21139.
4
Hand hygiene as the basic method of reducing infections (CDI) in a hospital environment.手卫生是减少医院环境中感染(CDI)的基本方法。
Ann Agric Environ Med. 2021 Dec 29;28(4):535-540. doi: 10.26444/aaem/131121. Epub 2021 Jan 4.
5
Pediatric Clostridioides difficile Infection: Diagnosis and Diagnostic Stewardship.小儿艰难梭菌感染:诊断和诊断管理。
J Pediatric Infect Dis Soc. 2021 Nov 17;10(Supplement_3):S16-S21. doi: 10.1093/jpids/piab054.
6
Red blood cell transfusion in critically-ill children and its association with outcome.危重症儿童的红细胞输血及其与结局的关系。
J Pak Med Assoc. 2021 Aug;71(8):1967-1971. doi: 10.47391/JPMA.110.
7
Costs Associated with the Treatment of Clostridioides Difficile Infections.艰难梭菌感染治疗相关成本。
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8
Level of Knowledge of Medical Staff on the Basis of the Survey in Terms of Risk Management, Associated with Infections.基于感染相关风险管理的医务人员知识水平调查
Int J Environ Res Public Health. 2021 Jul 1;18(13):7060. doi: 10.3390/ijerph18137060.
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Eur J Cancer Care (Engl). 2021 May;30(3):e13413. doi: 10.1111/ecc.13413. Epub 2021 Jan 28.