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新型冠状病毒肺炎与营养:关注慢性肾脏病。

COVID-19 and Nutrition: Focus on Chronic Kidney Disease.

机构信息

Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil; Graduate Program in Biological Sciences - Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro Rio de Janeiro, Brazil; Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil.

Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil.

出版信息

J Ren Nutr. 2023 Nov;33(6S):S118-S127. doi: 10.1053/j.jrn.2023.01.004. Epub 2023 Aug 25.

Abstract

Some chronic diseases, including chronic kidney disease (CKD), may be associated with poor outcomes, including a high rate of hospitalization and death after COVID-19 infection. In addition to the vaccination program, diet intervention is essential for boosting immunity and preventing complications. A healthy diet containing bioactive compounds may help mitigate inflammatory responses and oxidative stress caused by COVID-19. In this review, we discuss dietary interventions for mitigating COVID-19 complications, including in persons with CKD, which can worsen COVID-19 symptoms and its clinical outcomes, while diet may help patients with CKD to resist the ravages of COVID-19 by improving the immune system, modulating gut dysbiosis, mitigating COVID-19 complications, and reducing hospitalization and mortality. The concept of food as medicine, also known as culinary medicine, for patients with CKD can be extrapolated to COVID-19 infection because healthy foods and nutraceuticals have the potential to exert an important antiviral, anti-inflammatory, and antioxidant role.

摘要

一些慢性疾病,包括慢性肾脏病(CKD),可能与不良结局相关,包括 COVID-19 感染后的高住院率和死亡率。除了接种疫苗计划外,饮食干预对于增强免疫力和预防并发症至关重要。富含生物活性化合物的健康饮食可能有助于减轻 COVID-19 引起的炎症反应和氧化应激。在这篇综述中,我们讨论了饮食干预措施以减轻 COVID-19 并发症,包括 CKD 患者,因为 CKD 会加重 COVID-19 症状及其临床结局,而饮食可能通过改善免疫系统、调节肠道菌群失调、减轻 COVID-19 并发症以及降低住院率和死亡率来帮助 CKD 患者抵抗 COVID-19 的肆虐。对于 CKD 患者,将食物作为药物的概念,也称为烹饪医学,可以推广到 COVID-19 感染,因为健康食品和营养保健品有可能发挥重要的抗病毒、抗炎和抗氧化作用。

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