Emery H
Pediatr Clin North Am. 1986 Oct;33(5):1177-90. doi: 10.1016/s0031-3955(16)36114-4.
Systemic lupus erythematosus (SLE) is an uncommon childhood illness that is characterized by the formation of autoantibodies and immune complexes, which mediate inflammatory responses in multiple organ systems. Children who develop SLE are frequently very ill at the time of presentation and need careful evaluation to determine which organ systems are involved and how severely, meticulous control of medications to suppress active disease, and close monitoring to avoid complications from both the disease and its treatment.
系统性红斑狼疮（SLE）是一种罕见的儿童疾病，其特征是自身抗体和免疫复合物的形成，这些物质介导多个器官系统的炎症反应。患SLE的儿童在就诊时通常病情严重，需要仔细评估以确定哪些器官系统受累以及受累程度，精心控制药物以抑制疾病活动，并密切监测以避免疾病及其治疗引发的并发症。
