通过DNA-DNA杂交揭示的持续感染细胞培养物中蜱传脑炎病毒特异性序列。
Tick-borne encephalitis virus-specified sequences in persistently infected cell culture revealed by DNA-DNA hybridization.
作者信息
Andzhaparidze O G, Drynov I D, Bogomolova N N, Chelyapov N V, Boriskin Y S
出版信息
Experientia. 1979 May 15;35(5):601-2. doi: 10.1007/BF01960344.
PMID:376334
Abstract
Hybridization of DNA probe, obtained through DNA polymerase-mediated in vitro transcription of tick-borne encephalitis virus (TBEV) RNA, with DNA isolated from persistently infected with TBEV cell culture revealed 5.4 copies of viral genome per haploid set.
摘要
通过蜱传脑炎病毒（TBEV）RNA的DNA聚合酶介导的体外转录获得的DNA探针，与从持续感染TBEV的细胞培养物中分离的DNA杂交，结果显示每个单倍体基因组有5.4个病毒基因组拷贝。
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