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The emergence of tet(X) variants highlight challenges for the global genomic surveillance of tigecycline resistance.

作者信息

Rueda Furlan João Pedro, Fuentes-Castillo Danny, Guedes Stehling Eliana, Lincopan Nilton, Sellera Fábio P

机构信息

Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, São Paulo 14040-903, Brazil.

Departamento de Patología y Medicina Preventiva, Facultad de Ciencias Veterinarias, Universidad de Concepción, Chillán, Chile.

出版信息

Lancet Microbe. 2023 Nov;4(11):e857. doi: 10.1016/S2666-5247(23)00249-5. Epub 2023 Aug 24.

DOI:10.1016/S2666-5247(23)00249-5
PMID:37634526
Abstract
摘要

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Phenotypic Profiling of Tigecycline-resistant Klebsiella pneumoniae Strains Induced In vitro.体外诱导的耐替加环素肺炎克雷伯菌菌株的表型分析
Curr Microbiol. 2024 Dec 13;82(1):37. doi: 10.1007/s00284-024-04018-8.
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Emergence of plasmid-mediated tigecycline resistance (X4) gene in isolated from wild animals in captivity.在圈养野生动物分离株中出现质粒介导的替加环素耐药性(X4)基因。
Sci One Health. 2024 Apr 15;3:100069. doi: 10.1016/j.soh.2024.100069. eCollection 2024.
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A promising metabolite, 9-aminominocycline, restores the sensitivity of tigecycline against (X4)-positive .
一种有前景的代谢产物,9-氨基米诺环素,可恢复替加环素对X4阳性毒株的敏感性。
Front Microbiol. 2024 Jul 8;15:1432320. doi: 10.3389/fmicb.2024.1432320. eCollection 2024.
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Distribution and spread of tigecycline resistance gene (X4) in from different sources.不同来源的 中替加环素耐药基因(X4)的分布和传播。
Front Cell Infect Microbiol. 2024 Jun 28;14:1399732. doi: 10.3389/fcimb.2024.1399732. eCollection 2024.