某些7-β-羟基-γ-哌嗪丙基-8-苄氨基茶碱的化学和药理学性质
Chemical and pharmacological properties of some 7-beta-hydroxy-gamma-piperazinopropyl-8-benzylaminotheophylli nes.
作者信息
Gorczyca M, Pawłowski M, Mrozikiewicz A, Kozłowska T, Wasik A
出版信息
Pol J Pharmacol Pharm. 1986 Jan-Feb;38(1):85-90.
PMID:3763487
Abstract
In order to examine the circulatory and bronchospasmolytic activity, new 7-beta-hydroxy-gamma-N4-alkylpiperazinopropyl-8- benzylaminotheophyllines (1, 2, 3) were synthesized and converted to the water soluble dihydrochlorides (1a, 2a, 3a). They showed hypotensive and bronchodilatory effect.
摘要
为了研究循环和支气管解痉活性，合成了新型7-β-羟基-γ-N4-烷基哌嗪丙基-8-苄基氨基茶碱（1、2、3），并将其转化为水溶性二盐酸盐（1a、2a、3a）。它们显示出降压和支气管扩张作用。
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