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颈动脉内膜切除术:争议与建议

Carotid endarterectomy. Controversies and recommendations.

作者信息

Kistner R L, Ferris E B

出版信息

Postgrad Med. 1986 Sep 15;80(4):127-31. doi: 10.1080/00325481.1986.11699539.

Abstract

Carotid endarterectomy is a comparatively safe procedure for prevention of stroke in carefully selected patients with carotid stenosis. Generally, it is indicated in patients with hemispheric symptoms of transient ischemic attacks (TIAs), but it is more controversial in patients with non-hemispheric TIA symptoms or no symptoms. Emergency endarterectomy in patients with acute TIA symptoms is considered dangerous. Results of a series of 120 endarterectomies performed at Straub Clinic, Honolulu, confirm the benefits of elective endarterectomy when a meticulous operative technique is followed and intraoperative angiography and repair of defects are done. Prophylactic endarterectomy should not be performed unless a very low incidence (less than or equal to 3%) of combined major morbidity and mortality can be achieved.

摘要

对于精心挑选的有颈动脉狭窄的患者,颈动脉内膜切除术是一种相对安全的预防中风的手术。一般来说,有半球性短暂性脑缺血发作(TIA)症状的患者适合做该手术,但对于有非半球性TIA症状或无症状的患者,其争议性更大。有急性TIA症状的患者进行急诊内膜切除术被认为是危险的。在檀香山的斯特劳布诊所进行的一系列120例内膜切除术的结果证实,当采用精细的手术技术并进行术中血管造影和缺损修复时,择期内膜切除术是有益的。除非能实现极低的(小于或等于3%)主要发病率和死亡率合并发生率,否则不应进行预防性内膜切除术。

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