Department of Paediatrics, Hospital Universitario Virgen del Rocío, Seville, Spain.
Department of Dermatology, Hospital Universitario Virgen del Rocío, Seville, Spain.
Clin Pediatr (Phila). 2024 Jun;63(6):779-784. doi: 10.1177/00099228231193588. Epub 2023 Aug 27.
Vitiligo is a common disorder; however, its management is unknown by many primary-care doctors and pediatricians. Most articles focus on adults; we analyze the characteristics and impact on children. A single-center retrospective study was conducted over 10 years on 254 children diagnosed with vitiligo. About 50.4% were male with a mean age of 8.24 years. There was a slight predominance of nonsegmented vitiligo. About 12.59% had family history of vitiligo and 11.4% of autoimmune diseases. Around 15.7% patients presented other dermatological diseases and 9.05%, autoimmune diseases. No significant statistical differences were found when comparing age, sex, and type of vitiligo with other variables. Almost 96.06% received treatment with calcineurin inhibitors and 66.53% topical steroids. Around 77% obtained repigmentation, and out of the initial nonresponders, 16% responded to phototherapy. In general, our results concur with the scarce literature. A long-term follow-up of children with vitiligo is needed to identify treatment side effects and diseases associated.
白癜风是一种常见疾病；然而，许多初级保健医生和儿科医生并不了解其治疗方法。大多数文章都集中在成年人身上；我们分析了儿童的特征和影响。对 10 年来在 254 名被诊断为白癜风的儿童进行了一项单中心回顾性研究。大约 50.4%是男性，平均年龄为 8.24 岁。非节段性白癜风略占优势。约 12.59%有白癜风家族史，11.4%有自身免疫性疾病。约 15.7%的患者出现其他皮肤病，9.05%的患者有自身免疫性疾病。在比较白癜风的年龄、性别和类型与其他变量时，没有发现显著的统计学差异。几乎 96.06%的患者接受了钙调神经磷酸酶抑制剂治疗，66.53%的患者接受了局部皮质类固醇治疗。大约 77%的患者获得了色素沉着，在最初的无应答者中，16%的患者对光疗有反应。总的来说，我们的结果与稀缺的文献一致。需要对白癜风儿童进行长期随访，以确定治疗的副作用和相关疾病。
