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依托泊苷治疗相关的梭菌性肌坏死,表现为严重的大腿疼痛。

Clostridial myonecrosis in association with etoposide therapy presenting as severe thigh pain.

作者信息

Smith D, Harris M, Thatcher N

出版信息

Postgrad Med J. 1986 May;62(727):403-4. doi: 10.1136/pgmj.62.727.403.

Abstract

The case is described of a 68 year old man who was immunosuppressed as a result of receiving chemotherapy for small cell lung cancer and who presented with severe right thigh pain. This proved to be due to clostridial myonecrosis with none of the classical clinical features of clostridial infection. This is believed to be the first reported case of spontaneous clostridial infection associated with etoposide administration.

摘要

本文描述了一名68岁男性患者,因小细胞肺癌接受化疗而导致免疫抑制,出现严重的右大腿疼痛。结果发现这是由梭菌性肌坏死引起的,且没有梭菌感染的典型临床特征。据信这是首例与依托泊苷给药相关的自发性梭菌感染报告病例。

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本文引用的文献

1
Clostridial septicemia.
Cancer. 1972 Jan;29(1):215-21. doi: 10.1002/1097-0142(197201)29:1<215::aid-cncr2820290132>3.0.co;2-c.
3
Nontraumatic clostridial myonecrosis.非创伤性梭菌性肌坏死
Am J Med. 1978 Sep;65(3):542-6. doi: 10.1016/0002-9343(78)90782-9.

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