Abdildin Yerkin, Tapinova Karina, Salamat Azamat, Shaimakhanov Ramazan, Aitbayev Alisher, Viderman Dmitriy
School of Engineering and Digital Sciences, Nazarbayev University, Astana, Kazakhstan.
Nazarbayev University School of Medicine (NUSOM), Department of Biomedical Sciences, Astana, Kazakhstan.
Rom J Anaesth Intensive Care. 2023 Apr 20;30(1):43-50. doi: 10.2478/rjaic-2023-0006. eCollection 2023 Apr.
With the development of ultrasound-guided and laparoscopic techniques of rectus sheath block (RSB), regional analgesia promises to be efficient and safe. However, studies show controversial results. Our systematic review with meta-analysis aims to evaluate the effect of rectus sheath block in abdominal surgery.
We searched PubMed, Google Scholar, and the Cochrane Library from inception to October 2021 for randomised controlled trials written in English. We included studies on adult populations undergoing abdominal surgery. The primary outcomes of our meta-analysis were postoperative pain intensity and postoperative opioid consumption. Data analysis was conducted using the Review Manager software (RevMan, v. 5.4). Statistical heterogeneity was estimated by the I statistic. The methodological quality of the included studies was assessed using the Oxford quality scoring system (Jadad Scale).
Eight randomised controlled trials (RCTs) in English with a total of 386 patients were included in this meta-analysis. Patients in the RSB group did not consume fewer anaesthetics and opioids after abdominal surgery when compared with patients in the control group. In addition, postoperative pain intensity (out of 10) was not lower in the RSB group when compared with the control group. Finally, RSB did not improve the time to the first opioid/analgesic (min) compared with the non-RSB option.
There is no statistically significant evidence in favour of RSB over non-RSB in reducing anaesthetics and opioid consumption, postoperative pain intensity, and increasing time to first opioid/analgesic.
随着超声引导和腹腔镜腹直肌鞘阻滞(RSB)技术的发展,区域镇痛有望高效且安全。然而,研究结果存在争议。我们进行的这项系统评价及荟萃分析旨在评估腹直肌鞘阻滞在腹部手术中的效果。
我们检索了从创刊至2021年10月的PubMed、谷歌学术和考克兰图书馆,以查找用英文撰写的随机对照试验。我们纳入了针对接受腹部手术的成年人群的研究。我们荟萃分析的主要结局是术后疼痛强度和术后阿片类药物消耗量。使用Review Manager软件(RevMan,v. 5.4)进行数据分析。采用I统计量估计统计异质性。使用牛津质量评分系统(Jadad量表)评估纳入研究的方法学质量。
本荟萃分析纳入了8项英文随机对照试验(RCT),共386例患者。与对照组患者相比,腹直肌鞘阻滞组患者在腹部手术后并未减少麻醉剂和阿片类药物的使用量。此外,与对照组相比,腹直肌鞘阻滞组的术后疼痛强度(满分10分)并不更低。最后,与非腹直肌鞘阻滞方案相比,腹直肌鞘阻滞并未延长首次使用阿片类药物/镇痛药的时间(分钟)。
在减少麻醉剂和阿片类药物使用量、术后疼痛强度以及延长首次使用阿片类药物/镇痛药的时间方面,没有统计学上的显著证据支持腹直肌鞘阻滞优于非腹直肌鞘阻滞。