Veetil Pradeep Puthen, Puzhakkal Shikhil
Endocrine Surgery Department, Baby Memorial Hospital, 673004 Kozhikode, Kerala India.
Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):1647-1650. doi: 10.1007/s12070-023-03686-5. Epub 2023 Mar 23.
Total Thyroidectomy (TT) in true sense is not total as evidenced by remnant uptake in radio-iodine scans and serum thyroglobulin. The aim of this study is to assess the completeness of TT, operating time and recurrent laryngeal nerve injury with and without neuro-monitoring (IONM).
Cross sectional analytical study using retrospective data of patients undergoing total thyroidectomy for benign and malignant goiters. Surgeries performed by single surgeon. Patients undergoing TT (2015-22) were grouped into Group A (n = 400) and Group B (n = 400) based on use of IONM. Subgroup of patients (Group A1&B1) who had differentiated thyroid cancer were compared for completeness of thyroidectomy with DxWBS and serum thyroglobulin (TG). Group A and B were compared for operating time and incidence of RLN palsy.
Of the 800 RLN at risk transient RLN palsy was lower with IONM (p = 0.048). Mean operating time was significantly higher in Group-B(p = 0.0038). Subgroup A1 showed lower radio-active iodine uptake percentage, higher number of patients with negative scan, TG of < 1ng/mL indicating better completeness of TT.
Our study shows better completeness of thyroidectomy, lower incidence of transient RLN palsy and shorter operating time with IONM.
真正意义上的全甲状腺切除术(TT)并非完全切除,放射性碘扫描和血清甲状腺球蛋白中的残留摄取可证明这一点。本研究的目的是评估在有或没有神经监测(IONM)的情况下TT的完整性、手术时间和喉返神经损伤情况。
采用回顾性数据对因良性和恶性甲状腺肿接受全甲状腺切除术的患者进行横断面分析研究。手术由单一外科医生进行。根据是否使用IONM,将2015年至2022年接受TT的患者分为A组(n = 400)和B组(n = 400)。对患有分化型甲状腺癌的患者亚组(A1组和B1组)进行DxWBS和血清甲状腺球蛋白(TG)检查,比较甲状腺切除术的完整性。比较A组和B组的手术时间和喉返神经麻痹的发生率。
在800条有风险的喉返神经中,IONM组的暂时性喉返神经麻痹发生率较低(p = 0.048)。B组的平均手术时间明显更长(p = 0.0038)。A1亚组的放射性碘摄取百分比更低,扫描阴性的患者数量更多,TG<1ng/mL,表明TT的完整性更好。
我们的研究表明,使用IONM时甲状腺切除术的完整性更好,暂时性喉返神经麻痹的发生率更低,手术时间更短。